Patofisiologi Spinal Cord Injury

Ciatawi, Kartini; Tiffany, .

doi:10.55175/cdk.v49i9.2032

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…Secondary injury is triggered by the primary injury resulting in further chemical and mechanical damage to the spinal tissue causing excitotoxicity of the nerves due to calcium accumulation in the cells, as well as increasing reactive oxygen concentrations and glutamate levels. This damages the nucleic acids, proteins and phospholipids of the cells resulting in neurological dysfunction [24].…”

Section: Secondary Injurymentioning

confidence: 99%

The Effect of Using Robotic Lower Limb to Improve Endurance in Spinal Cord Injury: Literature Review

Pratama,

Sabilla,

Noviana

et al. 2023

Advances in Social Science, Education and Humanities Research

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The incidence of spinal cord injury is 90% due to traumatic causes, with traffic accidents being the leading cause, and falls being the second most common cause. Spinal cord injury occurs due to external physical trauma that damages the spinal cord or non-traumatic due to disease processes. Complications that occur are total or partial loss of locomotor function which can result in decreased endurance. One of the rehabilitation programs to restore endurance and walking function is by using robotic lower limb or exoskeleton robot. The purpose of this study was to explain the effect of using robotic lower limb to increase endurance in spinal cord injury cases. This research is a literature review study in narrative form, where 5 articles were reviewed after searching and selecting four databases. The review found a total of 83 subjects with a diagnosis of spinal cord injury aged 15 -75 years were given intervention using robotic lower limb with a frequency of 5 times per week with a duration of 30 -60 minutes. After the intervention was carried out for 2 -8 weeks, analysis of evaluation data found an increase in the ability to walk distance, and walking speed through assessment with 6MWT and 10MWT, so that it can be concluded that the provision of lower limb robotics is effective in increasing endurance in SCI patients..

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Section: Secondary Injurymentioning

confidence: 99%

The Effect of Using Robotic Lower Limb to Improve Endurance in Spinal Cord Injury: Literature Review

Pratama,

Sabilla,

Noviana

et al. 2023

Advances in Social Science, Education and Humanities Research

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Effectiveness of Pharmacotherapy in Reducing the Inflammation Process of Spinal Cord Injuries: A Systematic Review of Animal Studies

Subagio,

Wicaksono,

Asadullah

et al. 2024

The Scientific World Journal

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Background: Currently, there is no gold standard technique in SCI therapy. Although there have been many systematic reviews on the pharmacological treatment of inflammation in SCI, there has been no published discussion regarding the effectiveness of anti‐inflammatory pharmacotherapy when viewed from a neuroinflammatory pathway. This research aimed to examine an effective and reliable medication for decreasing inflammation in SCI and, where possible, identify effective pharmacotherapeutic treatment protocols.Methods: We searched SCOPUS, PubMed, PlosOne, and Science Direct, for experimental trials published in English. The keywords included (Pharmacotherapy OR pharmacology OR treatment) AND (traumatic spinal cord injury OR spinal cord OR traumatic OR hemisection of spinal cord OR compression OR traumatic spinal cord injury OR aneurysm clip OR hemisection of spinal cord OR sharp pin injury) AND (Side Effect therapy). In addition, the Basso–Beattie–Bresnahan (BBB) score was used to assess post‐SCI clinical progress.Results: Twelve pilot studies met the inclusion criteria. The highest BBB score was 15, and the best animal performance was tested after the average therapy was on the second week or 14th day. Three pharmacotherapies have fast effectiveness regarding BBB scores: calcitriol, lithium, and valproic acid. As well as a combination of pharmacotherapy therapy with surgical therapy also get significant results.Conclusions: The preliminary findings showed that many inflammatory pathways cause inflammatory agents to have their pathways for inhibition pathways, so they have different ways.

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Patofisiologi Spinal Cord Injury

Cited by 2 publications

References 9 publications

The Effect of Using Robotic Lower Limb to Improve Endurance in Spinal Cord Injury: Literature Review

The Effect of Using Robotic Lower Limb to Improve Endurance in Spinal Cord Injury: Literature Review

Effectiveness of Pharmacotherapy in Reducing the Inflammation Process of Spinal Cord Injuries: A Systematic Review of Animal Studies

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