Soymilk from TGX 923-2E soybean variety sprouted for 72hrs after 12 hours tap steeping was fortified with ferric ammonium citrate (Fe), calcium (Ca) and vitamin C (VC) according to Box-Wilson (1951) experimental design matrix. A central composite rotatable response surface design(CCRRSD) for K = 3 was employed to examine the linear, quadratic and cross product effects of independent process variable concentrations at 5 levels, Fe (1, 2, 3, 4 and 5mg/100ml), Ca (50, 100, 150, 200, and 250mg/100ml) and VC (8, 16, 24, 32 and 40mg/100ml) on the nutrient density of fortified soymilk stored at ambient temperature for 12 weeks. A total of 21 experimental runs were generated and the response surface data for each run were statistically regressed and analyzed for variance using Minitab computer software (version 11.21). Three-dimensional response surface figures were plotted with Matlab software (version R 2007b) to visualize the effects of fortificants variables on the responses. Results obtained showed that all the fortificants were significantly (p ≤ 0.05) linearly related to their respective responses. None of the response micronutrient met the respective RDI per serving except samples with variable combinations 2, 100, 32; 2, 200, 32; 4, 200, 32 and 3, 150, 40mg/100ml for ferric ammonium citrate, calcium carbonate and vitamin C respectively.