Pattern and outcome of gross congenital malformations at birth amongst newborns admitted to a tertiary hospital in northern Nigeria

Onankpa, BO; Adamu, Aliyu

doi:10.4314/njp.v41i4.9

Cited by 11 publications

(18 citation statements)

References 7 publications

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“…Neural tube defects were also the most common abnormality in some earlier studies. 4,12 The system with the highest frequency of abnormalities in some other Nigerian studies was the gastrointestinal. 5,16 This may be due to difference in the classification of disorders; the current study used the ICD-10 system which is recommended for uniformity in disease classification while other studies did not state the method used in the classification.…”

Section: Discussionmentioning

confidence: 99%

“…2 Between 2003 and 2007, the European Surveillance for Congenital Anomalies (EUROCAT) in 22 countries reported a incidence of 23.9 per 1000 births with 80% of births being live births. 3 In Nigeria, the reported incidence of congenital abnormalities vary from 2.1 to5.1% amongst live births in Northern Nigeria 4,5 to 15.9% of all births (including still births) in South west Nigeria.…”

Section: Introductionmentioning

confidence: 99%

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An 8-year review of major congenital abnormalities in a tertiary hospital in Lagos, Nigeria

Fajolu¹,

Ezenwa²,

Akintan³

et al. 2016

Nig. J. Paed.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

An 8-year review of major congenital abnormalities in a tertiary hospital in Lagos, Nigeria

Fajolu¹,

Ezenwa²,

Akintan³

et al. 2016

Nig. J. Paed.

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“…Some studies also show predominance of central nervous system among congenital anomalies. [19][20] . In the current study, Anorectal malformations are the most common congenital anomaly of gastro intestinal tract followed by Intestinal atresias.…”

Section: Discussionmentioning

confidence: 99%

Frequency and Pattern of GIT Anomalies in Neonates: A Retrospective Study at NICU Mayo Hospital Lahore

Bashir,

Javed,

Ameer

et al. 2022

PJMHS

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Aim: To acknowledge magnitude and spectrum of congenital anomalies of gastrointestinal tract in neonates and to establish possible factors resulting in these congenital anomalies. Material And Methods: The design of this study was Retrospective observational study. This study was conducted at NICU department of pediatric surgery King Edward medical university / Mayo hospital Lahore from June 2021 to May 2022. Neonates admitted in NICU department of pediatric surgery with gastrointestinal congenital anomaly were included in this study. Neonates having congenital anomaly other than GIT were excluded. Patient information regarding diagnosis and possible cause of congenital anomaly was noted on prescribed proforma. Results: During the study period total 256 neonates were admitted in neonatal ICU department of pediatric surgery Mayo hospital Lahore. Out of these 156(60.9%) neonates were having congenital anomalies of gastrointestinal tract while reaming 100(39.1%) neonates were having congenital anomalies of other structures. Most common congenital anomaly of GIT was anorectal malformations 35(22.4%) followed by Intestinal atresia’s in 30(19.2%). Conclusion: Congenital anomalies play an important role in neonatal mortality rate of any developing country like Pakistan. Chromosomal disorders, environmental and infectious factors are major contributing factors. Gastrointestinal tract anomalies are the most common anomalies of neonates with predominance of anorectal malformations. Antenatal care and timely interventions can reduce frequency of these anomalies. Keywords: Congenital anomalies, gastrointestinal tract, pattern.

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“…6,7 Furthermore, some hospital based studies conducted in different parts of Nigeria reported birth prevalence of congenital defects varying between 3.5 and 63 cases per 1000 births. [8][9][10][11][12][13] Some of these studies extracted data from delivery records 8,12,13 , paediatrics records 10,11 or both. 9 Majority of studies on the prevalence of birth defects in Nigeria focused on selected system defects like central nervous system defects (9.8 cases per 1000) 14 , orofacial defects (0.5 to 13.5 cases per 1000) 15,16 and congenital cardiac defects (0.5 cases per 1000).…”

Section: Introductionmentioning

confidence: 99%

Descriptive epidemiology of external structural birth defects in Enugu State, Nigeria

Izuchukwu

Nwokoye

Ossai

et al. 2022

gmj

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Objectives: To determine the birth prevalence, trend, and characteristics of external structural birth defects occurrence in Enugu Metropolis, Nigeria.Design: Cross-sectional study involving review of delivery records.Setting: The study was conducted at three tertiary hospitals, one public and two missionary, in Enugu Metropolis.Participants: Mothers and their babies delivered between 1 January 2009 and 31 December 2016 in the study facilities.Main outcome measures: Birth prevalence of defects presented as frequency/10,000 births. Other descriptive variables are presented as frequencies and percentages.Results: There were 21530 births with 133 birth defects (birth prevalence: 61.8/10,000 births) and 1176 stillbirths (stillbirth rate: 54.6/1000 births). The frequencies and birth prevalence (/10,000 births) of recorded defects were: Limb deformities 60(27.9), Neural tube defects (NTDs): 36(16.7), Urogenital system defects: 12(5.6), Gastrointestinal system defects 10(4.6) and Orofacial clefts 4(1.9). Birth defects occurrence showed a rising trend from 2009 to 2016. The mean (SD) age of mothers whose babies had Birth defects was 29.1(4.7) years. Only 62(46.6%) of 133 antenatal clinic folders of these women were traceable for further review. Eighteen (29.0%) had febrile illness in early pregnancy, 9(14.5%) had Malaria, 17(27.4%) had <4 antenatal clinic attendance, 7(11.3%) did not take folic acid and 6(9.7%) took herbal medications during pregnancy.Conclusions: Birth defects occurrence showed a rising trend with limb deformities and NTDs having the highest prevalence. Record keeping was poor at the facilities. Birth defects preventive interventions like folic acid supplementation for women-of-childbearing age should be promoted in Enugu Metropolis.

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Pattern and outcome of gross congenital malformations at birth amongst newborns admitted to a tertiary hospital in northern Nigeria

Cited by 11 publications

References 7 publications

An 8-year review of major congenital abnormalities in a tertiary hospital in Lagos, Nigeria

An 8-year review of major congenital abnormalities in a tertiary hospital in Lagos, Nigeria

Frequency and Pattern of GIT Anomalies in Neonates: A Retrospective Study at NICU Mayo Hospital Lahore

Descriptive epidemiology of external structural birth defects in Enugu State, Nigeria

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