Pattern of Meningitis in Al-Ain Medical District, United Arab Emirates—a Decadal Experience (1990–99)

Mahmoud, R. M.; Mahmoud, M.; Badrinath, Padmanabhan; Sheek-Hussein, Mohamud; Alwash, R; Nicol, Anne

doi:10.1053/jinf.2001.0937

Cited by 15 publications

(8 citation statements)

References 15 publications

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“…Our reported surveillance numbers of pneumococcal meningitis incidence were in the moderate range (0.7-14.4/100 000) [11,14,19,20] compared with that reported in developing nations (20/100 000) [32]. In a recent 5-year study [14], the incidence of IPD (24.4-53.5/100 000 population) was in the range expected for developing nations (10 to ∼100/100 000) [32,33].…”

Section: Discussionmentioning

confidence: 79%

“…A third study performed hearing tests only if parents or the physician suspected that hearing was impaired [22]. For most studies, there was no follow-up after hospital discharge, hence no long-term sequelae were reported; therefore, a causal relationship of complications with meningitis could only be inferred [12,19,21].…”

Section: Discussionmentioning

confidence: 99%

“…A similar descriptive retrospective study of the same area (UAE Al-Ain Medical District) was conducted during 1990-1999 [19]. Of 125 cases of bacterial meningitis reported, 20 (16%) were caused by S. pneumoniae.…”

Section: United Arab Emiratesmentioning

confidence: 99%

“…The CFR for pneumococcal meningitis ranged from a low of 0% in Qatar (<5 years) [20] and KSA (<13 years) [12] to a high of 22% (<15 years) in Yemen [24]. The percentage of pneumococcal meningitis cases that had residual morbidity ranged from a low of 10% (<5 years) in UAE [19] to a high of 62% (<12 years) in Qatar [20].…”

Section: Trends Across the Regionmentioning

confidence: 99%

See 3 more Smart Citations

Epidemiology of invasive pneumococcal disease in the Arabian Peninsula and Egypt

Shibl¹,

Memish²,

Pelton³

2009

International Journal of Antimicrobial Agents

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Section: Discussionmentioning

confidence: 79%

Section: Discussionmentioning

confidence: 99%

Section: United Arab Emiratesmentioning

confidence: 99%

Section: Trends Across the Regionmentioning

confidence: 99%

See 2 more Smart Citations

Epidemiology of invasive pneumococcal disease in the Arabian Peninsula and Egypt

Shibl¹,

Memish²,

Pelton³

2009

International Journal of Antimicrobial Agents

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“…The role of Haemophillus influenzae in causing sensorineural hearing loss following neonatal meningitis is well known and studies estimate an incidence of up to 25% cases develop hearing handicap [2]. Meningococcal meningitis too is well known to cause hearing loss in the adult population.…”

Section: Role Of Immunisationmentioning

confidence: 99%

Newer Frontiers in Hearing Rehabilitation

Singh

2006

Medical Journal Armed Forces India

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Laboratory-based surveillance of patients with bacterial meningitis in Egypt (1998–2004)

Afifi¹,

Wasfy²,

Azab³

et al. 2007

Eur J Clin Microbiol Infect Dis

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Laboratory-based surveillance for bacterial meningitis was conducted in a network of infectious disease hospitals in Egypt to better understand the epidemiology of this infection. Healthcare and laboratory personnel were trained in basic surveillance and microbiologic processing of cerebrospinal fluid (CSF) specimens. All bacterial isolates from CSF were confirmed and tested for antimicrobial susceptibility. PCR testing was performed on a random subset of purulent, culture-negative CSF specimens. Of 11,070 patients who met criteria for the case definition, 843 (8%) were culture positive (42% positive for Streptococcus pneumoniae, 20% for Haemophilus influenzae serotype b, 17% for each of Neisseria meningitidis and Mycobacterium tuberculosis, and 6% for other bacteria). Of 1,784 (46%) CSF specimens tested by PCR, 232 (13%) were positive for the first three major pathogens. Of N. meningitidis isolates, 52% belonged to serogroup A, 35% to serogroup B, and 4% to serogroup W135. S. pneumoniae isolates comprised 46 different serotypes, of which 6B, 1, 19A, 23F, and 6A were the most predominant. The overall case-fatality rate for culture-positive cases was 26% and was highest among patients with M. tuberculosis (47%). Factors significantly associated with death (p < 0.05) included admission to rural hospitals, long prodromal period, referral from other hospitals, antibiotic treatment prior to admission, and clear CSF (<100 cells/mm3). Susceptibility to ampicillin and ceftriaxone was observed in 44 and 100% of H. influenzae serotype b isolates and in 52 and 94% of S. pneumoniae isolates, respectively. This surveillance highlights the significant mortality and morbidity associated with bacterial meningitis in Egypt. Decision makers need to review current treatment guidelines and introduce appropriate vaccines for prevention and control of the disease.

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Pattern of Meningitis in Al-Ain Medical District, United Arab Emirates—a Decadal Experience (1990–99)

Cited by 15 publications

References 15 publications

Epidemiology of invasive pneumococcal disease in the Arabian Peninsula and Egypt

Epidemiology of invasive pneumococcal disease in the Arabian Peninsula and Egypt

Newer Frontiers in Hearing Rehabilitation

Laboratory-based surveillance of patients with bacterial meningitis in Egypt (1998–2004)

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