Pattern of Pseudomonas aeruginosa Drug Resistance in Tabriz Children Hospital

Ghorashi, Ziaaedin; Nezami, Nariman; Ghotaslou, Reza; Ghorashi, Sona

doi:10.3923/pjbs.2010.400.404

Cited by 8 publications

(6 citation statements)

References 12 publications

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“…(1) Regarding neonatal risk factors, this study shows that males (56%) were more often affected by birth trauma than females (44%), similar to Sameera.T.S. (9) Regarding birth weight, this study shows its significant influence in the occurrence of birth trauma, especially those babies with birth weight more than 4kg (macrosomic babies) which is similar to Ghorashi,et.al (10),Sameera. ( 9), Stoll BJ in 2007 (2), Mcintosh in 1998(4), Tsuji in 1997 (1), Overland in 2009 .…”

Section: Discussionsupporting

confidence: 72%

Neonatal Birth Traumas: Risk factors and types

Hameed,

Izzet

2010

JFacMedBagdad

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Background: Birth trauma is defined as injury to neonates resulting from mechanical forces (such as compression or traction) during the process of birth. Birth injury is used to denote avoidable and unavoidable mechanical and hypoxic-ischemic injury incurred by neonates during labor and delivery. Maternal, labor and infant factors can predispose to birth traumas. Many types of birth traumas can be found including intra and extra cranial, spinal, peripheral nerves, fractures and visceral. Patients and methods: A cross sectional study was done on 200 babies (100 babies for the study group and 100 babies for the control group), admitted to special care baby unit of Baghdad Teaching Hospital, during the period between 1st of October 2007 to the 30th of March 2008. Results: There was an increased percentage of birth trauma in preterm babies, large birth weight, mothers who were primigravida, had history of contracted pelvis, diabetes mellitus, prolong second stage of labor, abnormal fetal presentation, and shoulder dystocia. Trauma of cranium was the most common type of birth trauma, of which caput succedaneum (68%) was the most common one. Conclusions: Birth trauma is still a significant problem in this maternity ward causing some morbidity. The significant risk factors were macrosomia, prematurity and multiple pregnancies, primigravida, chronic maternal illness like diabetes mellitus, history of pelvic anomalies or contracted pelvis, prolonged labor especially the second stage, abnormal fetal presentation and shoulder dystocia. So we recommend assessment of the fetal weight, mother pelvis capacity and presentation before delivery, so that macrosomic fetus might be delivered by cesarean section, and prevent premature delivery, and better use of investigations like ultrasound,x-ray,CT scan for early diagnosis and further management of birth trauma.

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Section: Discussionsupporting

confidence: 72%

Neonatal Birth Traumas: Risk factors and types

Hameed,

Izzet

2010

JFacMedBagdad

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“…Fazeli et al indicated that resistance rate of P. aeruginosa against ceftazidime was 83.3%. The other study in Tabriz, Iran, declared that, 50% of P. aeruginosa strains were resistant against this group of antibiotics (14,15). In another study conducted by Hakemi-Vala, 62.95% of P. aeruginosa strains isolated from burnt wounds showed resistance against ceftazidim (16).…”

Section: Discussionmentioning

confidence: 99%

The Frequency of imp and vim Genes Among Pseudomonas aeruginosa Isolates From Children’s Medical Center of Tehran

Bejestani

Hakemi-Vala

Momtaheni

et al. 2015

Arch Clin Infect Dis

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Background:The first report of Pseudomonas aeruginosa ( P. aeruginosa ) carbapenem resistant strains, and especially the Metallo-BetaLactam (MBL) producers was from Japan, however, further reports were global. Objectives: The current study aimed to determine the frequency of vim and imp genes among P. aeruginosa MBL producer isolated from Children Medicinal Center during from 2011 to 2012. Materials and Methods: In the current descriptive study, 90 P. aeruginosa strains were collected from different clinical samples of children referring to Children's Medical Center of Tehran, Iran. All the isolates were identified and confirmed by the standard tests. Their resistance against common antibiotics was determined by disk diffusion method based on Clinical and Laboratory Standards Institute (CLSI) 2010 protocol. The MBL producers were screened by Combined Disk Diffusion test (CDDT) and using imp-imp/Ethylen Ediamine Tetra Acetic Acid (EDTA), and increasing of 7 mm≤ the diameter of inhibiting zone. The frequency of vim and imp genes was determined by Polymerase Chain Reaction (PCR). Results: Based on standard tests including Triple Sugar Iron Agar and Oxidation-Fermentation (OF) media and disability of the bacteria for glucose fermentation, 90 P. aeruginosa strains were confirmed. Their resistance against the following antibiotics was evaluated by disk diffusion method: 36.6% to cefotaxim, cefpodoxim and ticarcillin 33.3%, meropenem and aztreonam 32.2%, amikacin 28.8%, ciprofloxacin and ceftriaxon 27.7%, ceftazidime 22.3% and imipenem 15.5%. By PCR the frequency of imp gene with its 328 base pair band was (3.3%). The vim gene was not detected among the tested strains. Conclusions: Despite of high resistance of P. aeruginosa , the resistance rate of P. aeruginosa strains isolated from children in the current study was not high. Then accurate prescription of antibiotics can decrease the speed of resistance creation.

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“…Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme deficiency in the world (2) . A systematic review and a meta-analysis estimated an overall prevalence of G6PD deficiency at 4.9%, affecting 330 million people across the globe (3,4) . The global prevalence of G6PD deficiency is greater in regions that have been historically subjected to local malaria, including Africa, Asia, the Mediterranean, and the Middle East (3,4) .…”

Section: Introductionmentioning

confidence: 99%

“…A systematic review and a meta-analysis estimated an overall prevalence of G6PD deficiency at 4.9%, affecting 330 million people across the globe (3,4) . The global prevalence of G6PD deficiency is greater in regions that have been historically subjected to local malaria, including Africa, Asia, the Mediterranean, and the Middle East (3,4) . Iran is among countries that report a high prevalence of G6PD deficiency, ranging from 2.28% to 30.80% (4,5) .…”

Section: Introductionmentioning

confidence: 99%

“…The global prevalence of G6PD deficiency is greater in regions that have been historically subjected to local malaria, including Africa, Asia, the Mediterranean, and the Middle East (3,4) . Iran is among countries that report a high prevalence of G6PD deficiency, ranging from 2.28% to 30.80% (4,5) . Phototherapy is a well-known standard method for treating neonatal hyperbilirubinaemia.…”

Section: Introductionmentioning

confidence: 99%

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The effect of phototherapy on neonatal calcium and bilirubin levels: a comparison between patients with low and normal G6PD levels

Sheikh¹,

Ostad-Rahimi²

2023

Pediatr Med Rodz

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Introduction: Iran is among countries that report a higher prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency, ranging from 2.28% to 30.80%. This study aimed to estimate the general prevalence of G6PD deficiency in newborns with jaundice who were hospitalised in southeast Iran. Methods: This was a prospective study. A total of 100 newborns (boys and girls) with hyperbilirubinaemia, presented to Amir Al-Mo’menin Hospital in 2006 and 2007, were selected for the study. Age, gender, weight, time of jaundice, the maximum level of direct bilirubin, and the total level of bilirubin among the newborns were recorded, and the data were analysed by SPSS. Results: A total of 100 jaundice neonates, including 46 girls and 54 boys, were enrolled. Twenty-two percent of these patients, including 18 (82%) boys and 4 (18%) girls, showed low levels of G6PD. The overall mean bilirubin level was 15.45 ± 3.43 mg/dL among neonates with low G6PD levels, while it was 19.21 ± 3.34 mg/dL in patients with normal G6PD levels, which showed a significant difference (p < 0.05). Conclusion: The prevalence of G6PD deficiency in neonates with jaundice in our study was 22%, which was higher compared to other regions. We propose G6PD deficiency screening for the prevention of its complications. We also suggest assessing calcium levels following phototherapy, given the higher prevalence of hypocalcaemia.

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Pattern of Pseudomonas aeruginosa Drug Resistance in Tabriz Children Hospital

Cited by 8 publications

References 12 publications

Neonatal Birth Traumas: Risk factors and types

Neonatal Birth Traumas: Risk factors and types

The Frequency of imp and vim Genes Among Pseudomonas aeruginosa Isolates From Children’s Medical Center of Tehran

The effect of phototherapy on neonatal calcium and bilirubin levels: a comparison between patients with low and normal G6PD levels

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