Pattern of recurrence of nonsyndromic keratocystic odontogenic tumors

Berge, Trond Inge; Helland, Saedeh B.; Sælen, Andreas; Øren, Maria; Johannessen, Anne Christine; Skartveit, Liv; Grung, Bjarte

doi:10.1016/j.oooo.2016.01.004

Cited by 26 publications

(26 citation statements)

References 23 publications

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“…In our study all the relapse occurred in lesion with cortical bone perforation, while none of the OKCs without this characteristic recurred. Berge et al described the pattern of recurrence of nonsyndromic OKCs and observed that relapse appeared earlier and frequently for those lesions with bone perforation [14]. A similar finding was earlier described for other aggressive lesion such as ameloblastoma [15] and the authors proposed to resect adjacent soft tissue to prevent recurrence.…”

Section: Discussionmentioning

confidence: 58%

Factors influencing the recurrence of keratocysts: monocentric study

Giovacchini

Bensi

Paradiso

et al. 2019

J Oral Med Oral Surg

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Introduction: The purpose of the study was to retrospectively analyse the recurrence rate of odontogenic keratocysts and to identify eventual features of the lesions that may influence recurrence. Material and methods: This was a retrospective study carried out for a period of 3 years. The medical records of patients treated in our institution were analysed to identify all the cases of odontogenic keratocysts. Results: A total of 16 odontogenic keratocysts were recorded. These lesions were treated with simple enucleation with or without adjuvant Carnoy's solution. The relapse occurred in 4 patients treated with simple enucleation and in none of the patients that underwent enucleation and Carnoy's solution application. The kind of treatment appeared not to influence recurrence rate at statistical analysis. Conclusions: Odontogenic keratocyst is a lesion with a locally aggressive behavior and a high tendency to relapse. This tendency of recurrence may be greater with syndromic presentation of odontogenic keratocyst, with soft tissue involvement, and with teeth proximity to the lesion. The application of Carnoy's solution may be useful to minimize recurrence rate in those odontogenic keratocysts with an aggressive clinical behavior and secondly may be used for all the other lesions treated with simple enucleation that experienced relapse.

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Section: Discussionmentioning

confidence: 58%

Factors influencing the recurrence of keratocysts: monocentric study

Giovacchini

Bensi

Paradiso

et al. 2019

J Oral Med Oral Surg

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“…They may be positioned adjacent to the lateral aspect of the tooth root similar to a lateral periodontal cyst [18]. In a review of the radiographic aspects of 1138 OKC's, reported in several studies, including recurrent and syndromic OKC's, we found that 672 were unilocular (59%), 342 multilocular (30%), 202 had a smooth or well-defined border (18%), while 70 had a scalloped border (6%) [18,[27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45]. In many instances, the radiological aspect was not reported.…”

Section: Pathogenesis Of Okc'smentioning

confidence: 99%

Conservative Treatment of Primary and Nonsyndromic Odontogenic Keratocyst: An Overview of the Practice

Silva¹,

Homem²

2018

Int J Oral Dent Health

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and has decided to rename this lesion to Odontogenic Keratocyst again (OKC) [1]. The motivation for this policy change, however, is lacking. The OKC is potentially a very aggressive lesion (Figure 1) and this name change may bring about some confusion among surgeons and tends to lessen the alertness among surgeons to treat this lesion adequately [2]. Apart from its high recurrence rate after treatment [3], Emerson, et al. described the extension of two recurrent OKC's in the mediastinum, via the neck [4]. Other authors have already reported the extension of three OKC's into the base of the skull [5-7], two OKC's penetrating into the temporalis muscle [8,9] and two OKC's into the masseter muscle [10,11]. Four case reports have been published showing recurrent OKC's in a bone graft [12-15]. Regular, ordinary, odontogenic cysts do not behave this way [2].

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“…Odontogenic keratocyst (OKC) is a benign intraosseous cystic lesion of the gnathic bones which probably originates from the remnants of the dental lamina (2,3). In 2005, the classification of Tumors of the Head and Neck of the World Health Organization (WHO) classified this lesion as a neoplasm derived from the odontogenic epithelium, naming it as a Keratocyst Odontogenic Tumor (2)(3)(4)(5). However, the recent WHO classification had gone back and reclassified this lesion as an odontogenic cyst.…”

Section: Introductionmentioning

confidence: 99%

The recurrence of odontogenic keratocysts in pediatric patients is associated with clinical findings of Gorlin-Goltz Syndrome

Silva¹,

Rolim²,

Silva³

et al. 2020

Med Oral

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Background: Odontogenic keratocyst (OKC) is an odontogenic developmental cyst that presents distinct clinical behavior. This lesion has been described as dental cysts with keratinization since the 1930s, however the term "OKC" was established in 1956. This study aims to determine the frequency and features of OKC in children aged 0 to 14 years in an oral pathology service in Brazil. Material and Methods: A retrospective study was performed to review cases of OKC in children diagnosed between 1986 and 2017. Clinical data were evaluated from medical records (gender, race, age, anatomical location, treatment, radiographic findings and follow-up). Results: Ninety-seven cases of OKC were diagnosed in a 31-year-period in all age groups and 10 were found in children (10.3%). Age ranged from 2 to 14 years (mean age=10.5±3.5), with 8 males and 2 females. The most frequent location was the anterior region of the mandible (n=4). Patients were predominantly asymptomatic. Moreover, in two children, clinical findings of Gorlin-Goltz Syndrome were observed. The most commonly used treatment was enucleation followed by curettage. In all cases of Gorlin-Goltz Syndrome were observed recurrences and occurrence of new keratocysts. Conclusion: Although uncommon in pediatric patients, OKC should be considered a differential diagnosis in cases of osteolytic lesions in gnathic bones. Thus, the periodic assessment of children by dentists and pediatricians is essential to get a correct diagnosis and early treatment to avoid greater mutilation of these patients.

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Pattern of recurrence of nonsyndromic keratocystic odontogenic tumors

Cited by 26 publications

References 23 publications

Factors influencing the recurrence of keratocysts: monocentric study

Factors influencing the recurrence of keratocysts: monocentric study

Conservative Treatment of Primary and Nonsyndromic Odontogenic Keratocyst: An Overview of the Practice

The recurrence of odontogenic keratocysts in pediatric patients is associated with clinical findings of Gorlin-Goltz Syndrome

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