“…identified de novo variations in FOXP1 , GRIN2B , SCN1A , LAMC3, and rare inherited CNTNAP2 variations (De Rubeis et al., 2014; O'Roak et al., 2011). Three genes were found in ASD probands with two de novo variations in each of these genes: BRCA2 , FAT1, and KCNMA1 (Neale et al., 2012). These studies also found significant enrichment of de novo variations in five ASD candidate genes including STXBP1 , MEF2C , KIRREL3 , RELN, and TUBA1A (Neale et al., 2012).…”