Patterns of Concerns Among Hematological Cancer Survivors

Abstract

Background: Advances in treatment for hematological cancers warrant greater attention on survivorship concerns. Objective: The aims of this study were to describe survivorship concerns among hematological cancer survivors, identify subgroups of survivors with distinct classes of concerns, and examine sociodemographic and clinical differences across subgroups. Methods: We conducted a cross-sectional analysis of data from 1160 hematological cancer survivors, who rated their degree of concern regarding 20 physical, emotional, and practical changes. Clusters of concerns were identified using latent class analysis. Associations between respondent characteristics and cluster membership were calculated using multinomial logistic regression. Results:Survivors had a mean of 7.5 concerns (SD, 4.6; range, 0-19), the most frequent being fatigue/tiredness (85.4%); anxiety, stress, and worry about cancer returning (70.2%); and changes to concentration/memory (55.4%). Three distinct classes of concerns were identified: class 1 (low, 47.0%), characterized by low endorsement of most concerns, apart from fatigue; class 2 (moderate, 32.3%), characterized by high endorsement of a combination of concerns across domains; and class 3 (high, 20.7%), characterized by the highest number of concerns out of the 3 identified classes, including greater endorsement of concerns relating to sexual well-being. Class membership was differentiated by survivor age, sex, marital status, and diagnosis. Conclusions: Three distinct patterns of concerns were detected in a large sample of hematological cancer survivors. Patterns of concerns could be differentiated by survivor characteristics. Implications for

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“…Some literature suggests that older adults with AML have different care needs compared to young or middle-aged adults with AML [ 16 , 17 ]. Older adults with AML are more at risk for fragility and mobility issues compounded with the natural course of aging and can be even more susceptible to infectious diseases [ 18 , 19 ]. Caregivers of older adults with AML may provide different levels and types of support, especially if the patient has severe levels of fatigue, decreased dependence, and physical mobility difficulties [ 18 ].…”

“…Older adults with AML are more at risk for fragility and mobility issues compounded with the natural course of aging and can be even more susceptible to infectious diseases [ 18 , 19 ]. Caregivers of older adults with AML may provide different levels and types of support, especially if the patient has severe levels of fatigue, decreased dependence, and physical mobility difficulties [ 18 ]. Therefore, caregivers of older adults with AML may require additional training on managing fatigue and mobility issues at home than caregivers of younger adults with AML.…”

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