Patterns of drug use and sensation‐seeking among adolescents in Norway

Pedersen, Willy; Clausen, Sten-Erik; Lavik, Nils Johan

doi:10.1111/j.1600-0447.1989.tb10274.x

Cited by 55 publications

(22 citation statements)

References 8 publications

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“…For example, in a study of SS and drug use in 1027 Norwegian male and female high school students aged 16-19 years, Pedersen et al [59] found that DIS correlated highly with alcohol, while TAS predicted tobacco use. In contrast, high scores on ES predicted use of cannabis and tranquilizers.…”

Section: Sensation Seeking As a Risk Factor For Behavioral Problemsmentioning

confidence: 96%

The Sensation Seeking Trait and Substance Use: Research Findings and Clinical Implications

Bardo¹,

Williams²,

Dwoskin³

et al. 2007

CPSR

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Sensation seeking (SS) is a personality trait defined by a need to seek novel sensations and experiences, accompanied by a willingness to take risks for the sake of such experiences. Various measures of SS have been developed and validated, including a scale specifically for children. Among different populations, SS has been associated with the expression of various health-related risk behaviors, most notably substance use and abuse. Evidence from basic research with laboratory animals and from human clinical studies indicates that high sensation seekers may have an overactive mesocorticolimbic dopamine system relative to low sensation seekers. While the precise molecular mechanisms underlying SS remain to be elucidated, evidence suggests that low levels of monoamine oxidase activity, as well as altered dopamine receptor and dopamine transporter expression and function may play a role. Since altered monoamine function has been implicated in various psychiatric disorders, and since SS has been associated with some of these disorders, clinicians may find that SS offers a useful adjunct in promoting effective patient care and improving patient counseling. This may be especially useful in treating children, adolescents and young adults, as the risk for substance use and abuse is an especially relevant concern during this developmental period.

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Section: Sensation Seeking As a Risk Factor For Behavioral Problemsmentioning

confidence: 96%

The Sensation Seeking Trait and Substance Use: Research Findings and Clinical Implications

Bardo¹,

Williams²,

Dwoskin³

et al. 2007

CPSR

View full text Add to dashboard Cite

show abstract

“…41 Family History. Alcoholism typology research has shown higher sensation seeking 33 and psychopathology (anxiety, depression, antisocial personality disorder) 23 in early onset group and (less often) a di¡erential pattern of psychopathology (antisocial personality in early onset group and anxiety and depression in late onset group). 3,4 The insigni¢cant di¡erence in our study may be due to a relatively low genetic contribution to opioid dependence, as compared to alcoholism.…”

Section: Comparison With Alcohol Typologymentioning

confidence: 99%

Age at Onset Typology in Opioid‐dependent Men: An Exploratory Study from India

Mattoo

Basu

2003

American J Addict

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This study attempted to apply age at onset typology in ICD-10-diagnosed opioid dependence. The sample is comprised of eighty men seeking treatment at an addiction clinic in India. The measures included a sociodemographic and clinical profile, Severity of Opioid Dependence Questionnaire, Sensation Seeking Scale, Multiphasic Personality Questionnaire (MPQ), and Family History Assessment Module. Application of k-means cluster analysis led to the emergence of two cluster types: early onset (mean age at onset 21 years) and late onset (mean age at onset 27 years). The early onset group was characterized by a significantly younger current age, more urban and unemployed subjects, younger ages at the onset of opioid use and dependence, a higher severity of opioid use, a higher lifetime use of sedatives and tobacco, younger ages at the onset of dependence on alcohol and cannabis, higher sensation seeking, and higher global psychopathology in terms of MPQ. Other less differentiating features were higher family history of psychiatric illness (including substance abuse), longer duration of opioid use and dependence, and higher lifetime use of cannabis. These results show the age at onset typology in opioid dependence to be feasible and to have some similarities to age at onset typology in alcoholism.

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“…Males typically have higher SS scores than females (Zuckerman et al, 1978), but the link between SS and drug use is found in both sexes, in general. The link between high SS and drug abuse has been found with many drugs including nicotine, alcohol, opioids, hallucinogens, and stimulants (Pedersen et al, 1989; Bobes et al, 2002). Several studies have established that HSs are more sensitive to the subjective, reinforcing and/or physiological effects of drugs: the drugs studied included alcohol (de Wit et al, 1987; Fillmore et al, 2009), amphetamines (Hutchison et al, 1999; Kelly et al, 2006, 2009; Stoops et al, 2007), methylphenidate (Chait, 1994), benzodiazepines (Kelly et al, 2009), and nicotine (Perkins et al, 2000).…”

Section: Introductionmentioning

confidence: 99%

A possible link between sensation-seeking status and positive subjective effects of oxycodone in healthy volunteers

Zacny

2010

Pharmacology Biochemistry and Behavior

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Sensation seeking is a personality trait that is linked to use and abuse of drugs. Laboratory studies have established that high sensation seekers, as measured by different instruments, are more likely to report abuse liability-related subjective effects from drugs such as nicotine, alcohol, and d-amphetamine than low sensation seekers. One class of drugs that has not been studied to date in this fashion is opioids. Accordingly, a retrospective analysis encompassing five studies that examined oxycodone effects, including its abuse liability-related effects, was conducted in subjects categorized as high or low sensation seekers. In addition, because there appear to be sex differences in how males and females respond to opioids, this factor was taken into account in the analysis. Seventy one subjects who scored on the lower end (15 and 19 low sensation seeking males and females, respectively) or the higher end (23 and 14 high sensation seeking males and females) of the Disinhibition subscale of the Sensation Seeking Scale-Form V were studied for their responses to 0, 10, and 20 mg of oral oxycodone. Ratings of “pleasant bodily sensations” were significantly higher after oxycodone administration than placebo only in male and female high sensation seekers. Ratings of “take again,” “drug liking,” “carefree,” and “elated (very happy)” also tended to differentiate high from low sensation seekers although Group × Dose interactions were only marginally significant with the latter three ratings. Male and female low sensation seekers and female high sensation seekers reported dysphoric effects (e.g., ratings of nauseated) particularly after administration of the 20-mg oxycodone dose. The results of this analysis provide suggestive evidence that high sensation seekers are more likely to experience greater positive subjective effects from oxycodone than low sensation seekers, but likelihood of experiencing negative effects is more complex (involving both sensation seeking status and sex).

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Patterns of drug use and sensation‐seeking among adolescents in Norway

Cited by 55 publications

References 8 publications

The Sensation Seeking Trait and Substance Use: Research Findings and Clinical Implications

The Sensation Seeking Trait and Substance Use: Research Findings and Clinical Implications

Age at Onset Typology in Opioid‐dependent Men: An Exploratory Study from India

A possible link between sensation-seeking status and positive subjective effects of oxycodone in healthy volunteers

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