Patterns of Hand Grip Strength and Detection of Strength Loss in Patients Undergoing Bone Marrow Transplantation: A Feasibility Study

Abstract

Weakness increases risk for falls. Patients may experience as much as 50% strength loss during the course of hospitalization for BMT. Strength loss occurs in the conditioning phase for some patients.

Fall risk factors in hospitalized bone marrow transplant patients: A systematic review

“…GVHD is usually treated with corticosteroids, which often cause muscle atrophy and may lead to muscle weakness (Morishita, Kaida, Yamauchi, Sota, et al, 2013). For example, in a study, researchers found that patients undergoing BMT experienced a strength loss using grip strength test (Sayre et al, 2017).…”

“…GVHD is usually treated with corticosteroids, which often cause muscle atrophy and may lead to muscle weakness (Morishita, Kaida, Yamauchi, Sota, et al., 2013). For example, in a study, researchers found that patients undergoing BMT experienced a strength loss using grip strength test (Sayre et al., 2017). Although this study did not specifically focus on fall or fall risk, future researchers who study fall risk may include hand grip strength and examine its relationship with falls.…”

“…Although this study did not specifically focus on fall or fall risk, future researchers who study fall risk may include hand grip strength and examine its relationship with falls. Including grip strength into routine assessment patients undergoing BMT may also help to increase awareness of the loss of strength of patients undergoing BMT have over the course of their treatment, and the potential risk for falls (Sayre et al., 2017). Grady (2020) used an orthostatic vital signs algorithm as a method to decrease falls in patients undergoing BMT by identifying patients undergoing BMT with orthostatic hypotension.…”

“…different risk factors when compared to other patients with oncological conditions and the general hospital patient population. It should be taken into account when nurses create care plans, educate patients, and evaluate risk factors and effectiveness of fall prevention measures in order to meet the needs of patients undergoing BMT(Grady et al, 2020;Sayre et al, 2017).Nurses providing care to patients undergoing BMT need to assess and increase nurse surveillance on allogeneic transplant patients, patients undergoing BMT over 65 years old, and patients receiving hypnotic, anxiolytic, and steroid medication. Also, patients in the postengraftment period, especially those experiencing muscle weakness, should be closely supervised.…”

A Scoping Review on Outcomes and Outcome Measurement Instruments in Rehabilitative Interventions for Patients with Haematological Malignancies Treated with Allogeneic Stem Cell Transplantation

“…It is a widely used outcome in HSCT research, something that is probably due to the practicability of its measurement. Other authors underline the importance of this outcome during hospitalization for allogeneic HSCT since detecting strength loss can improve fall prevention [ 61 ]. However, in addition to handgrip strength, eight other aspects of strength were measured in the studies that we included (i.e., isokinetic leg performance, knee extension strength, muscle strength, peripheral muscle strength, strength, strength capacity, trunk strength, and upper limb muscle strength).…”