Patterns of patient specific dosimetry in total body irradiation

Akino, Yuichi; McMullen, Kevin P.; Das, Indra J.

doi:10.1118/1.4795335

Cited by 12 publications

(14 citation statements)

References 40 publications

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“…9,16 It is therefore encouraging that with the approach described in this study, it is possible to plan and deliver almost all doses within this range (Fig. 3).…”

Section: Discussionmentioning

confidence: 81%

See 1 more Smart Citation

Benefits of online in vivo dosimetry for single-fraction total body irradiation

Eaton¹,

Warry²,

Trimble³

et al. 2014

Medical Dosimetry

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“…9,16 It is therefore encouraging that with the approach described in this study, it is possible to plan and deliver almost all doses within this range (Fig. 3).…”

Section: Discussionmentioning

confidence: 81%

“…Akino et al 16 suggested that corrections required for singlefraction treatments might be applied halfway through the treatment. However, the discrepancies reported for their moving- table Table 3 Comparison of measured and expected doses, for this study (also shown in Fig.…”

Section: Discussionmentioning

confidence: 99%

Benefits of online in vivo dosimetry for single-fraction total body irradiation

Eaton¹,

Warry²,

Trimble³

et al. 2014

Medical Dosimetry

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“…Previous reports, however, show that achieving these tolerances can prove challenging. Actual differences in administered dose have been observed to deviate greater than 35% from the prescription . As such, field homogeneity testing plays an important role in quality assurance testing of 60 Co irradiators.…”

Section: Introductionmentioning

confidence: 99%

Technical Note: Quality assurance and relative dosimetry testing of a ⁶⁰Co total body irradiator using optical imaging

et al. 2019

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Purpose The aim of this study was to create an optical imaging‐based system for quality assurance (QA) testing of a dedicated Co‐60 total body irradiation (TBI) machine. Our goal is to streamline the QA process by minimizing the amount time necessary for tests such as verification of dose rate and field homogeneity. Methods Plastic scintillating rods were placed directly on the patient treatment couch of a dedicated TBI 60Co irradiator. A tripod‐mounted intensified camera was placed directly adjacent to the couch. Images were acquired over a 30‐s period once the cobalt source was fully exposed. Real‐time image filtering was used; cumulative images were flatfield corrected as well as background and darkfield subtracted. Scintillators were used to measure light‐radiation field correspondence, dose rate, field homogeneity, and symmetry. Dose rate effects were measured by modifying the height of the treatment couch and scintillator response was compared to ionization chamber (IC) measurements. Optically stimulated luminesce detector (OSLD) used as reference dosimeters during field symmetry and homogeneity testing. Results The scintillator‐based system accurately reported changes in dose rate. When comparing normalized output values for IC vs scintillators over a range of source‐to‐surface distances, a linear relationship (R2 = 0.99) was observed. Normalized scintillator signal matched OSLD measurements with <1.5% difference during field homogeneity and symmetry testing. Beam symmetry across both axes of the field was within 2%. The light field was found to correspond to 90 ± 3% of the isodose maximum along the longitudinal and latitudinal axis, respectively. Scintillator imaging output results using a single image stack requiring no postexposure processing (needed for OSLD) or repeat manual measurements (needed for IC). Conclusion Imaging of scintillation light emission from plastic rods is a viable and efficient method for carrying out TBI 60Co irradiator QA. We have shown that this technique can accurately measure field homogeneity, symmetry, light‐radiation field correspondence, and dose rate effects.

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“…A translational couch technique maintains a static beam and gantry, while the patient travels under the linac on a specialized translational couch 11. A homogeneous dose can be delivered by varying the speed of the couch movement 12, 13. Custom‐made lung shields and beam spoilers may still be required for these techniques.…”

Section: Introductionmentioning

confidence: 99%

Volumetric modulated arc therapy for total body irradiation: A feasibility study using Pinnacle³ treatment planning system and Elekta Agility™ linac

Symons

Morrison

Parry

et al. 2018

J Applied Clin Med Phys

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A study was undertaken to explore the use of volumetric modulated arc therapy (VMAT) for total body irradiation (TBI). Five patient plans were created in Pinnacle3 using nine 6 MV photon dynamic arcs. A dose of 12 Gy in six fractions was prescribed. The planning target volume (PTV) was split into four subsections for the head, chest, abdomen, and pelvis. The head and chest beams were optimized together, followed by the abdomen and pelvis beams. The last stage of the planning process involved turning all beams on and performing a final optimization to achieve a clinically acceptable plan. Beam isocenters were shifted by 3 or 5 mm in the left–right, anterior–posterior, and superior–inferior directions to simulate the effect of setup errors on the dose distribution. Treatment plan verification consisted of ArcCheck measurements compared to calculated doses using a global 3%/3 mm gamma analysis. All five patient plans achieved the planning aim of delivering 12 Gy to at least 90% of the target. The mean dose in the PTV was 12.7 Gy. Mean lung dose was restricted to 8 Gy, and a dose reduction of up to 40% for organs such as the liver and kidneys proved feasible. The VMAT technique was found to be sensitive to patient setup errors particularly in the superior–inferior direction. The dose predicted by the planning system agreed with measured doses and had an average pass rate of 99.2% for all arcs. VMAT was found to be a viable treatment technique for total body irradiation.

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Patterns of patient specific dosimetry in total body irradiation

Cited by 12 publications

References 40 publications

Benefits of online in vivo dosimetry for single-fraction total body irradiation

Benefits of online in vivo dosimetry for single-fraction total body irradiation

Technical Note: Quality assurance and relative dosimetry testing of a ⁶⁰Co total body irradiator using optical imaging

Volumetric modulated arc therapy for total body irradiation: A feasibility study using Pinnacle³ treatment planning system and Elekta Agility™ linac

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Patterns of patient specific dosimetry in total body irradiation

Cited by 12 publications

References 40 publications

Benefits of online in vivo dosimetry for single-fraction total body irradiation

Benefits of online in vivo dosimetry for single-fraction total body irradiation

Technical Note: Quality assurance and relative dosimetry testing of a 60Co total body irradiator using optical imaging

Volumetric modulated arc therapy for total body irradiation: A feasibility study using Pinnacle3 treatment planning system and Elekta Agility™ linac

Contact Info

Product

Resources

About

Technical Note: Quality assurance and relative dosimetry testing of a ⁶⁰Co total body irradiator using optical imaging

Volumetric modulated arc therapy for total body irradiation: A feasibility study using Pinnacle³ treatment planning system and Elekta Agility™ linac