Paving a Shorter Path Towards Diagnosis: A Case on Adult Onset Still’s Disease from Pakistan

Abstract

Adult onset Still’s disease (AOSD) is a rare clinical entity with unknown etiology, characterized by arthritis, fever, erythematous rash, and other systemic presentations. We report a case of a 21-year-old male who presented with high spiking fever, dry cough, generalized body ache, arthralgia, and an erythematous rash. He was eventually diagnosed to have AOSD based on the Yamaguchi criteria, after a month of visiting three different healthcare facilities and receiving two misdiagnoses and treatment regimes not specific to his diagnosis. The patient immediately responded to prednisoloneand was healthy upon discharge.

Bibliometrics analysis on the research status and trends of adult-onset Still’s disease: 1921-2021

“…In the absence of markers for specific diagnosis and curative effect evaluation ( 25 ), AOSD is primarily diagnosed by excluding other diseases ( 26 ). For the possibility of misdiagnosis in AOSD ( 27 ), the average delay time of diagnosis is about four months ( 28 ). Yamaguchi criteria ( 29 ) have the highest diagnostic sensitivity of 92%, followed by Fautrel criteria ( 30 ) (87%) and Cush criteria ( 31 ) (80%).…”