“…Huang et al 27 compared the prediction accuracy of quadratic discriminant analysis (QDA), 91 K-nearst neighbor (KNN), 92 ANN, XGBoost (XGB), 93 and SVM models. Raman spectra of the plasma-derived extracellular vesicles of patients with various degrees of CAD were used to train and predict CAD: stable nonobstructive plaques (SP), non-ST-elevation myocardial infarction, ST-elevation myocardial infarction CAD, and healthy controls without CAD.…”