Pediatric Chest MRI: A Review

Kapur, Savinay; Bhalla, Ashu Seith; Jana, Manisha

doi:10.1007/s12098-018-02852-w

Cited by 20 publications

(26 citation statements)

References 20 publications

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“…So far, MRI has mainly been studied for perfusion and lung volume measurements, 21 more recently also to study the structural lung sequelae in CDH 9 . Expertise gained from other diseases like CF will expand the field of MRI lung imaging in the near future 22 …”

Section: Discussionmentioning

confidence: 99%

“…9 Expertise gained from other diseases like CF will expand the field of MRI lung imaging in the near future. 22 CT imaging was done without controlled inspiration and expiration scans. Although volume control is not essential for all CT scoring, 23 spirometer-guided inspiratory CT scans are considered superior for the objective evaluation of bronchiectasis and to detect regions of trapped air and hypoperfusion.…”

Section: T a B L E 4 Correlation Between Ct Scores And Clinical Parammentioning

confidence: 99%

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Chest CT scoring for evaluation of lung sequelae in congenital diaphragmatic hernia survivors

Beel

Aukland

Boon

et al. 2020

Pediatric Pulmonology

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Objectives Data on long‐term structural lung abnormalities in survivors of congenital diaphragmatic hernia (CDH) is scarce. The purpose of this study was to develop a chest computed tomography (CT) score to assess the structural lung sequelae in CDH survivors and to study the correlation between the CT scoring and clinical parameters in the neonatal period and at 1 year of follow‐up. Methods A prospective, clinical follow‐up program is organised for CDH survivors at the University Hospital of Leuven including a chest CT at the age of 1 year. The CT scoring used and evaluated, named CDH‐CT score, was adapted from the revised Aukland score for chronic lung disease of prematurity. Results Thirty‐five patients were included. All CT scans showed some pulmonary abnormalities, ranging from very mild to severe. The mean total CT score was 16 (IQR: 9‐23), with the greatest contribution from the subscores for decreased attenuation (5; IQR: 2‐8), subpleural linear and triangular opacities (4; IQR: 3‐5), and atelectasis/consolidation (2; IQR: 1‐3). Interobserver and intraobserver agreement was very good for the total score (ICC coefficient > 0.9). Total CT score correlated with number of neonatal days ventilated/on oxygen as well as with respiratory symptoms and feeding problems at 1 year of age. Conclusion The CDH‐CT scoring tool has a good intraobserver and interobserver repeatability and correlates with relevant clinical parameters. This holds promise for its use in clinical follow‐up and as outcome parameter in clinical interventional studies.

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Section: Discussionmentioning

confidence: 99%

Section: T a B L E 4 Correlation Between Ct Scores And Clinical Parammentioning

confidence: 99%

Chest CT scoring for evaluation of lung sequelae in congenital diaphragmatic hernia survivors

Beel

Aukland

Boon

et al. 2020

Pediatric Pulmonology

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“…Magnetic resonance imaging modality has several limitations in early childhood such as the need of sedation, being late and expensive to perform. However, MRI provides novel technical advantages by parallel imaging, shared echo-technique and rotating phase encoding to deal with cardiac and respiratuar motion in addition to its previously known superiority as providing functional and chemical information (13). CT provides higher geometrical resolution due to thin slices but has a general limitation as radiation exposure.…”

Section: Discussionmentioning

confidence: 99%

Sağlikli Çocuklarda Medi̇asti̇nal Lenf Gangli̇onlari; Yaşa Göre Siklik, Boyut Araliği Ve Dağilim

Bayramoğlu¹,

Yekeler²

2020

J Istanb Fac Med

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This study was presented in ''Pediatri Günleri Congress (2019, İstanbul) as oral presentation and has been choosen for the best oral presentation award. ÖZET Amaç: Klinik olarak anlamlı lenf nodları (LN) hakkında karar vermek çok önemlidir. Mediastinal LNları lokasyon, boyut ve yaş gruplarına göre değerlendirdik. Gereç ve Yöntem: Travma sonrası radyoloji bölümüne yönlendirilen 150 çocuğun kontrastlı göğüs bilgisayarlı tomografi taramaları retrospektif olarak değerlendirildi. Tüm katılımcılar her biri otuz çocuğu içeren beş yaş grubuna ayrıldı (0-24, 25-60, 61-120, 121-180 ve 181-216 ay). En büyük LNlarının kısa ve uzun eksendeki çapları konumları, yaş ve cinsiyetlerine göre değerlendirildi. SPSS 22 programı ile Kolmogorov-Smirnov testi, t testi, Spearman korelasyon analizi ve tanımlayıcı istatistikler çalışıldı.

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“…MRI is a well-established technique especially suitable for the assessment of soft tissues and characterized by the extraordinary advantage, among others, of using nonionizing radiofrequency electromagnetic radiations [126,127].…”

Section: Magnetic Resonance Imaging (Mri) and Pet/mrimentioning

confidence: 99%

Molecular Imaging of Pulmonary Inflammation and Infection

Giraudo

Evangelista

Fraia

et al. 2020

IJMS

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Infectious and inflammatory pulmonary diseases are a leading cause of morbidity and mortality worldwide. Although infrequently used in this setting, molecular imaging may significantly contribute to their diagnosis using techniques like single photon emission tomography (SPET), positron emission tomography (PET) with computed tomography (CT) or magnetic resonance imaging (MRI) with the support of specific or unspecific radiopharmaceutical agents. 18F-Fluorodeoxyglucose (18F-FDG), mostly applied in oncological imaging, can also detect cells actively involved in infectious and inflammatory conditions, even if with a low specificity. SPET with nonspecific (e.g., 67Gallium-citrate (67Ga citrate)) and specific tracers (e.g., white blood cells radiolabeled with 111Indium-oxine (111In) or 99mTechnetium (99mTc)) showed interesting results for many inflammatory lung diseases. However, 67Ga citrate is unfavorable by a radioprotection point of view while radiolabeled white blood cells scan implies complex laboratory settings and labeling procedures. Radiolabeled antibiotics (e.g., ciprofloxacin) have been recently tested, although they seem to be quite unspecific and cause antibiotic resistance. New radiolabeled agents like antimicrobic peptides, binding to bacterial cell membranes, seem very promising. Thus, the aim of this narrative review is to provide a comprehensive overview about techniques, including PET/MRI, and tracers that can guide the clinicians in the appropriate diagnostic pathway of infectious and inflammatory pulmonary diseases.

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Pediatric Chest MRI: A Review

Cited by 20 publications

References 20 publications

Chest CT scoring for evaluation of lung sequelae in congenital diaphragmatic hernia survivors

Chest CT scoring for evaluation of lung sequelae in congenital diaphragmatic hernia survivors

Sağlikli Çocuklarda Medi̇asti̇nal Lenf Gangli̇onlari; Yaşa Göre Siklik, Boyut Araliği Ve Dağilim

Molecular Imaging of Pulmonary Inflammation and Infection

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