Pediatric Displaced Fractures of the Lateral Condyle of the Humerus Treated Using High Strength, Bioactive, Bioresorbable F-u-HA/PLLA Pins

Takada, Naoya; Otsuka, Takanobu; Suzuki, Hiroyuki; Yamada, Kentaro

doi:10.1097/bot.0b013e318269ba8e

Cited by 17 publications

(7 citation statements)

References 9 publications

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“…There has been some study into the popular topic of using bioresorbable implants, which could potentially solve this problem. A study of eight patients by Takada et al [15] showed no skin erosion and no infections in the use of bioresorbable F-u-HA/PLLA pins. The pin can be trimmed flush as it does not require to be left proud for removal, and therefore, the risk of erosion is reduced.…”

Section: Discussionmentioning

confidence: 97%

Buried versus unburied Kirschner wires in the management of paediatric lateral condyle elbow fractures

Ormsby

Walton²,

Robinson³

et al. 2016

Journal of Pediatric Orthopaedics B

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There is little consensus on whether Kirschner wire (K-wire) burial is preferable in the management of paediatric lateral humeral condyle fractures. We identified 124 patients from May 2008 to August 2014. Sixty received buried K-wires and 64 received unburied wires. We found no significant difference in the infection rates between groups, but a high rate of skin erosion (23%) in the buried group, with a subsequent high rate of infection in this subgroup (40%). We found a strong association of wire erosion following early surgery. There is a considerable cost saving associated with using unburied wires. We therefore recommend the routine use of unburied wires.

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Section: Discussionmentioning

confidence: 97%

Buried versus unburied Kirschner wires in the management of paediatric lateral condyle elbow fractures

Ormsby

Walton²,

Robinson³

et al. 2016

Journal of Pediatric Orthopaedics B

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“…Regarding osteoconduction, numerous studies using rabbit models have demonstrated the osteoconductive ability and bone bonding features of u-HA/PLLA [7,8,9]. Thus, u-HA/PLLA is used extensively as bone plates and screws for osteosynthesis in different surgical specialties such as orthopedics, plastic surgery, or thoracic surgery [10,11,12,13]. However, these animal experiments only tested the osteoconductive ability of u-HA/PLLA using a rod inserted fully into the knee, such that there was full bone contact.…”

Section: Introductionmentioning

confidence: 99%

Bone Regeneration Potential of Uncalcined and Unsintered Hydroxyapatite/Poly l-lactide Bioactive/Osteoconductive Sheet Used for Maxillofacial Reconstructive Surgery: An In Vivo Study

et al. 2019

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Uncalcined and unsintered hydroxyapatite/poly l-lactide (u-HA/PLLA) material has osteoconductive characteristics and is available for use as a maxillofacial osteosynthetic reconstruction device. However, its bone regeneration ability in the maxillofacial region has not been fully investigated. This study is the first to assess the bone regenerative potential of osteoconductive u-HA/PLLA material when it is used for repairing maxillofacial bone defects. A total of 21 Sprague-Dawley male rats were divided into three groups—the u-HA/PLLA, PLLA, or sham control groups. A critical size defect of 4 mm was created in the mandible of each rat. Then, the defect was covered with either a u-HA/PLLA or PLLA sheet on the buccal side. The rats in each group were sacrificed at 2, 4, or 8 weeks. The rats’ mandibles were sampled for histological analysis with hematoxylin and eosin staining, histomorphometry, and immunohistochemistry with Runx2 and osteocalcin (OCN) antibody. The amount of newly formed bone in the u-HA/PLLA group was significantly higher than that of the PLLA group. The expression of Runx2 and OCN in the u-HA/PLLA group was also significantly higher. These results demonstrate that the u-HA/PLLA material has excellent bone regenerative ability and confirm its applicability as a reconstructive device in maxillofacial surgery.

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“…Biodegradable implants have been applied for various pediatric orthopaedic fixation without the need for routine implant removal as is performed for metallic hardware [9] , [10] , [11] . Implants made of F-u-HA/PLLA have advantages over PLLA-only implants, including: expectation of greater initial mechanical strength [9] , implant radio-opacity enables radiographic observation during healing, good biocompatibility throughout the resorption process, and direct binding to surrounding bone without intervention involving fibrous tissue [10] . F-u-HA/PLLA implants may cause foreign body reactions associated with PLLA releasement.…”

Section: Discussionmentioning

confidence: 99%

Isolated trochlea osteochondral fracture of the distal humerus in a 6-year-old patient surgically fixed using biodegradable pins: A case study with over 3 years of follow-up

Tsukamoto

Mae²,

Hirabayashi³

et al. 2022

Trauma Case Reports

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Pediatric Displaced Fractures of the Lateral Condyle of the Humerus Treated Using High Strength, Bioactive, Bioresorbable F-u-HA/PLLA Pins

Abstract: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.

Cited by 17 publications

References 9 publications

Buried versus unburied Kirschner wires in the management of paediatric lateral condyle elbow fractures

Buried versus unburied Kirschner wires in the management of paediatric lateral condyle elbow fractures

Bone Regeneration Potential of Uncalcined and Unsintered Hydroxyapatite/Poly l-lactide Bioactive/Osteoconductive Sheet Used for Maxillofacial Reconstructive Surgery: An In Vivo Study

Isolated trochlea osteochondral fracture of the distal humerus in a 6-year-old patient surgically fixed using biodegradable pins: A case study with over 3 years of follow-up

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