Pediatric Reference Intervals for 34 Biochemical Analytes in Urban School Children and Adolescents

Jagarinec, Nada; Flegar-Meštrić, Zlata; Šurina, Branka; Vrhovski-Hebrang, Danijela; Preden-Kereković, Vladimira

doi:10.1515/cclm.1998.055

Cited by 36 publications

(36 citation statements)

References 45 publications

(15 reference statements)

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“…Women had a mean weight of 71.5 kg (ss8.9 kg) and a mean height of 1.64 m (ss0.05 m) and men had a mean weight of 86.1 kg (ss10.6 kg) and a mean height of 1.87 m (ss0.05 m). Results of standard laboratory tests for all subjects were within previously established reference intervals for the Croatian population (4,5,7). This study was performed with permission from the Ethical Committee of Medical School University of Zagreb, Croatia, and written consent was obtained from all participants.…”

Section: Reference Individuals and Samplessupporting

confidence: 68%

Applicability of common reference intervals for serum creatinine concentrations to the Croatian population

Flegar-Meštrić

Perkov

Šimonović

et al. 2009

Clinical Chemistry and Laboratory Medicine

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Background: In accordance with an ongoing activity for worldwide harmonization based on traceability in laboratory methods, the goal of this study was to validate the applicability of recommended ''common'' reference intervals for serum creatinine concentrations using a specific enzymatic method to the Croatian population. Methods:The reference group consisted of 240 healthy subjects (120 males and 120 females), between 18 and 74 years of age (median 57 years), who were selected in accordance with the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) recommendations. Creatinine in serum was measured using the creatinine enzymatic assay (Olympus OSR61204) that was standardized to the isotopic dilution mass spectrometry (IDMS) method and National Institute of Standards and Technology (NIST) Standard Reference Material (SRM) 967. In addition, creatinine was measured using a kinetic Jaffe method (Olympus OSR6178) standardized to NIST SRM 909b level 2 standard. Results: Method comparison between enzymatic creatinine (x) and the Jaffe kinetic method (y) gave the following P/B equation for the entire group (ns240): ys1.00xq17.00; rs0.968. Reference intervals for serum creatinine (central 95th percentiles) obtained using the enzymatic creatinine

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Section: Reference Individuals and Samplessupporting

confidence: 68%

Applicability of common reference intervals for serum creatinine concentrations to the Croatian population

Flegar-Meštrić

Perkov

Šimonović

et al. 2009

Clinical Chemistry and Laboratory Medicine

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“…Increase in creatinine with the advancement of age for both sexes could be due to muscle degradation with age. Higher creatinine levels in males than in females may be due to the greater muscle mass in males than females [14]. The higher UA in males relative to females could be explained by the higher clearance rate in females than in males [15].…”

Section: Results Are Expressed As Means (X) ± Standard Deviation (Sd)mentioning

confidence: 99%

Reference Ranges for Some Biochemical Parameters in Adult Kenyans

Waithaka¹,

Njagi²,

Ngeranwa³

et al. 2009

Int J Health Res

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an online international journal allowing free unlimited access to abstract and full-text of published articles. The journal is devoted to the promotion of health sciences and related disciplines (including medicine, pharmacy, nursing, biotechnology, cell and molecular biology, and related engineering fields). It seeks particularly (but not exclusively) to encourage multidisciplinary research and collaboration among scientists, the industry and the healthcare professionals. It will also provide an international forum for the communication and evaluation of data, methods and findings in health sciences and related disciplines. The journal welcomes original research papers, reviews and case reports on current topics of special interest and relevance. All manuscripts will be subject to rapid peer review. Those of high quality (not previously published and not under consideration for publication) will be published without delay. The maximum length of manuscripts should normally be 10,000 words (20 single-spaced typewritten pages) for review, 6,000 words for research articles, 3,000 for technical notes, case reports, commentaries and short communications. Submission of Manuscript:The International Journal of Health Research uses a journal management software to allow authors track the changes to their submission. All manuscripts must be in MS Word and in English and should be submitted online at http://www.ijhr.org. Authors who do not want to submit online or cannot submit online should send their manuscript by e-mail attachment (in single file) to the editorial office below. Submission of a manuscript is an indication that the content has not been published or under consideration for publication elsewhere. Authors may submit the names of expert reviewers or those they do not want to review their papers. Abstract PURPOSE: To establish the reference ranges of some biochemical parameters for adult Kenyan population. Enquiries METHODS:In a prospective involving 1100 healthy blood donors (age: 18-55 yr) in Kenyatta National Hospital, Kenya reference ranges of some biochemical analytes were constructed by using the parametric methods to estimate 2.5 and 97.5 percentiles of distribution. RESULTS:The reference ranges of the analytes were: alanine aminotransferase ( . Age differences in the established reference ranges were observed in ALT, ALB, CREAT, ALP and UA in males and in ALT, ALB, and CREAT in females. Gender differences were observed in ALT, AST, ALB, CREAT and UA in the 18-28 yr old, ALT, AST, ALB, SOD and UA in 29-39 yr old and AST, ALB, and UA in 40-50 yr old. CONCLUSION: Age and sex specific reference ranges of some biochemical parameters were established some of which were different from those reported in literature. There therefore the need for each clinical chemistry laboratory to establish its own ranges.

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“…Other authors have found a di¡erence between male and female values after puberty for both these enzymes, as is found in adults. 21,22 Our lack of discrimination may be due to a relatively small sample size for these age groups. Transformed results gave acceptable intervals in these cases even with the remaining data, which were still skewed.…”

Section: ^22mentioning

confidence: 94%