Pediatric Renal Transplantation in Oman: A Single-center Experience

Riyami, Mohamed S Al; Saidi, Sulaiman Al; Ghaithi, Badria Al; Maskari, Anisa Al; Lala, Sadiq; Mohsin, Nabil; Hirshikesan, Lekha; Kalbani, Naifain Al

doi:10.5001/omj.2018.03

Cited by 7 publications

(15 citation statements)

References 29 publications

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“…The NAPRTCS report published in 2014 presented that the majority of pediatric recipients of renal transplantation were between 13 and 17 years old (39.2%) followed by 6‐ to 12‐year‐olds (32.6%), and rest were under the age of five . The most common etiology of ESRD was congenital nephrotic syndrome, renal dysplasia, nephronophthisis, and posterior urethral valves which are similar to the reported literature in this region and NAPRTCS report …”

Section: Discussionsupporting

confidence: 86%

“…The reported 1‐ and 5‐year graft survival rates range between 93% and 95% (from living donors) and 77% and 85% (from deceased donors) . The published graft survival rates from the region include 78.0% (5‐year follow‐up) reported in a study from Oman, 88% (5‐year follow‐up) from Jordan, and 89.2% (10‐year follow‐up) from Iran . The five‐year patient survival rates observed in our study were 96.7% which is promising compared to the 10‐year follow‐up published reports of 89.2% (10‐year) from India and Iran, 92.3% (10‐year) from single‐center study in Japan, and 92.0% (10‐year) from a single‐center study in France .…”

Section: Discussionmentioning

confidence: 99%

“…region and NAPRTCS report. 13,14 At our center, 70% of the recipients were on peritoneal dialysis prior to renal transplantation followed by hemodialysis. The choice of initial modality of dialysis at a nephrology center differs from country to country and depends on the available technical and nursing support.…”

Section: Effect Of Transplantation On Renal Functionmentioning

confidence: 99%

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Good outcome of the single‐center pediatric kidney transplant program in Abu Dhabi

Kumar

Al-Ismaili

Ilyas

et al. 2019

Pediatric Transplantation

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Renal transplantation is the treatment of choice for ESRD in children. It is associated with better quality of life, growth of children, and improved long‐term survival. The aim of the study was to evaluate the outcomes of pediatric renal transplantation at a tertiary care center in UAE. A retrospective chart review was undertaken for all the pediatric renal transplants performed at Sheikh Khalifa Medical City, Abu Dhabi, UAE, over the past 9 years. The study evaluated the demographic data, outcomes, and complications of pediatric renal transplantation. The post‐transplantation outcomes including surgical complications, documented infections, graft rejection, graft and patient survival, effect on growth, and eGFR were reviewed. Between 2010 and 2018, 30 pediatric patients underwent renal transplantation. The follow‐up period ranged from 1 to 9 years with a mean of 3.3 years. The mean age of the patients at the time of transplant was 9.8 years, and 56.7% were males. Prior to the transplantation, the majority of the recipients were on peritoneal dialysis (70.0%). Main source of renal donation at our center was from LRD, chiefly from parents. Patient survival at 1 and 5 years was 100% and 96.7%, respectively. Graft survival at 1 and 5 years was 96.7% and 83.3%, respectively. During the 9‐year follow‐up period, 5 (16.7%) recipients experienced rejection episode. This study demonstrates that during 5‐year period, pediatric kidney transplantation program has achieved optimal patient (96.7%) and graft (83.3%) survival rates and is comparable to well‐established centers.

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Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Section: Effect Of Transplantation On Renal Functionmentioning

confidence: 99%

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Good outcome of the single‐center pediatric kidney transplant program in Abu Dhabi

Kumar

Al-Ismaili

Ilyas

et al. 2019

Pediatric Transplantation

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“…Pada tahun 1993, Oman menerbitkan undang-undang tentang transplantasi yang hanya membolehkan transplantasi dengan donor living related, melarang komersialisasi transplantasi, dan membolehkan donor diperoleh dari jenazah. 6 Di Brazil pada tahun 1998 hingga 2010 telah dilakukan transplantasi ginjal pada 62 anak berusia < 15 tahun, 7 di Afrika transplantasi ginjal pada anak dilakukan pada tahun 1968 di rumah sakit di Cape Town, Afrika Selatan. 8 Di Jakarta, transplantasi ginjal pada anak pertama kali dilakukan di Rumah Sakir Dr. Cipto Mangunkusomo pada bulan Maret 2013. dan memberikan hasil yang baik, tidak terdapat reaksi rejeksi maupun komplikasi.…”

Section: Pembahasanunclassified

“…Donor living related terdiri atas ibu (48,0%), ayah (19,0%), bibi (17,0%), paman (11%), dan saudara kandung (7%). 6 Di Jakarta, donor untuk kesebelas transplan anak tersebut terdiri atas 4 nonrelated living donor dan 7 orang related living donor, yaitu 5 orang donor ayah dan 2 orang donor ibu. Hingga saat ini transplanatsi ginjal menggunakan donor hidup dan tidak ada yang menggunakan donor jenazah.…”

Section: Pembahasanunclassified

Pengalaman Transplantasi Ginjal pada Anak di Jakarta

Pardede

Hidayati

Ambarsari

et al. 2019

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Latar belakang.Transplantasi ginjal merupakan terapi yang efektif untuk penyakit ginjal kronik (PGK) stadium 5 atau gagal ginjal terminal. Transplantasi ginjal di dunia pertama kali dilakukan pada tahun 1950an. Di Indonesia, transplantasi ginjal pada orang dewasa telah dilakukan pada tahun 1977 dan semakin berkembang dan telah dilakukan di beberapa kota di Indonesia. Transplantasi ginjal pada anak pertama kali dilakukan di Rumah Sakit Dr. Cipto Mangunkusomo pada bulan Maret 2013, terhadap seorang anak lelaki berusia 13 tahun dengan gagal ginjal terminal yang disebabkan sindrom nefrotik, dengan ginjal yang diperoleh dari non-related living donor. Ini merupakan transplantasi ginjal yang pertama kali dilakukan pada anak di Indonesia.Tujuan. Melaporkan data tentang kegiatan transplantasi ginjal yang dilakukan di Jakarta.Metode. Penelitian ini merupakan penelitian retrospektif yang mengambil data dari catatan medis. Hingga tahun 2018 telah dilakukan 11 kali transplantasi ginjal pada 10 orang anak terdiri atas 9 laki-laki dan 1 perempuan, dengan 1 kasus re-transplan. Rentang usia adalah 8-18 tahun, dengan penyakit dasar terdiri atas sindrom nefrotik (3 anak), dan ginjal hipoplasia (7 anak). Donor untuk kesebelas transplan anak tersebut terdiri atas 4 non-related living donor dan 7 orang related living donor, yaitu 5 orang donor ayah dan 2 orang donor ibu. Hasil. Di antara 10 pasien transplan, 3 orang menggunakan biaya pribadi atau asuransi swasta dan 8 orang dengan biaya dari Badan Penyelenggara Jaminan Sosial (BPJS). Hingga bulan Agustus 2018, di antara kesepuluh anak tersebut, 7 orang hidup dan di antaranya 2 orang mengalami rejeksi pada tahun ke-3 (1 orang konversi kembali ke hemodialisis dan 1 orang telah menjalani re-transplan). Tiga pasien meninggal akibat infeksi berat.Kesimpulan. Transplantasi ginjal di Rumah Sakit Dr. Cipto Mangunkusomo dimulai pada tahun 2013, dengan donor hidup yang sebagian besar berasal dari orangtua, dengan pembiayaan sebagian besar menggunakan BPJS.

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