This work aimed to assess the biomechanics, using the finite element method (FEM), of traditional titanium Morse taper (MT) dental implants compared to one-piece implants composed of zirconia, polyetheretherketone (PEEK), carbon fiber-reinforced PEEK (CFR-PEEK), or glass fiber-reinforced PEEK (GFR-PEEK). MT and one-piece dental implants were modeled within a mandibular bone section and loaded on an oblique force using FEM. A MT implant system involving a Ti6Al4V abutment and a cp-Ti grade IV implant was compared to one-piece implants composed of cp-Ti grade IV, zirconia (3Y-TZP), PEEK, CFR-PEEK, or GFR-PEEK. Stress on bone and implants was computed and analyzed while bone remodeling prediction was evaluated considering equivalent strain. In comparison to one-piece implants, the traditional MT implant revealed higher stress peak (112 MPa). The maximum stresses on the onepiece implants reached $80 MPa, regardless their chemical composition. MT implant induced lower bone stimulus, although excessive bone strain was recorded for PEEK implants. Balanced strain levels were noticed for reinforced PEEK implants of which CFR-PEEK one-piece implants showed proper biomechanical behavior. Balanced strain levels might induce bone remodeling at the peri-implant region while maintaining low risks of mechanical failures. However, the strength of the PEEKbased composite materials is still low for long-term clinical performance.biomechanics, dental implants, dental materials, finite elements analysis, implant design 1 | INTRODUCTION Titanium dental implants have been increasingly used to replace missing teeth within a high long-term success rate as reported in literature. [1][2][3][4] Dental implants are often composed of two components: the endosseous implant itself and the abutment. The connection between traditional abutment and endosseous implants can be commonly achieved by screwing the abutment in the inner implant surfaces up to a maximum adequate torque or within a Morse taper (MT) effect, in which an applied preload generates stresses that keep the components attached to each each other. 5,6 At last, a single-or multi-unit prosthesis is cemented and/or screwed over the abutment to replace the coronal dental structure. MT implant systems typically reveal higher mechanical stability due to their connection on contacting surfaces and distribution of stresses to the bone. [5][6][7][8] However, the microgap existing between