Peer review of the pesticide risk assessment of the active substance clopyralid

Arena, Maria; Auteri, Domenica; Barmaz, Stefania; Brancato, Alba; Brocca, Daniela; Bura, László; Cabrera, Luis Carrasco; Chiusolo, Arianna; Civitella, Consuelo; Marques, Danièle Court; Crivellente, Federica; Ctverackova, Lucie; Lentdecker, Chloé De; Egsmose, Mark; Erdős, Zoltán; Fait, Gabriella; Ferreira, Lucien; Greco, Luna; Ippolito, Alessio; Istace, Fréderique; Jarrah, Samira; Kardassi, Dimitra; Leuschner, Renata; Lostia, Alfonso; Lythgo, Christopher; Magrans, José Oriol; Medina, Paula; Mineo, Desire; Miron, Ileana; Molnár, Tünde; Padovani, Laura; Morte, Juan Manuel Parra; Pedersen, Ragnor; Reich, Hermine; Sacchi, Angela; Santos, Miguel; Serafimova, Rositsa; Sharp, Rachel; Stanek, Alois; Streissl, Franz; Sturma, Juergen; Szentes, Csaba; Tarazona, José; Terron, Andrea; Theobald, Anne; Vagenende, Bénédicte; Dijk, Joanke Van; Villamar‐Bouza, Laura

doi:10.2903/j.efsa.2018.5389

Cited by 7 publications

(35 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…From the rotational crop metabolism studies which were assessed in the framework of the EU pesticides peer review, it was concluded that the same metabolic pattern is observed across all rotational crops and that this corresponds with the findings in primary crops with clopyralid and conjugated clopyralid being the major residues (EFSA, 2018d). The studies covered three plant back intervals (PBI), with quantifiable amounts reported at PBI of 30 days (except for radish roots) and identification performed in all plant parts.…”

Section: Residues In Plantsmentioning

confidence: 55%

“…The metabolism of clopyralid in primary crops belonging to the group of root crops (sugar beets), leafy crops (head cabbage), pulses/oilseeds (oilseed rape) has been investigated in the framework of the previous MRL application and EU pesticides peer review (EFSA, 2011, 2018d). In the context of the peer review, a data gap was identified for the clarification of the unknown polar compound observed in mature samples of rape seed and sugar beet.…”

Section: Residues In Plantsmentioning

confidence: 99%

“…Clopyralid is proposed to be used on crops that can be grown in rotation with other crops. It is considered to be low to medium persistent, forming no metabolites at levels triggering identification or further assessment; it does not accumulate in soil (EFSA, 2018d).…”

Section: Residues In Plantsmentioning

confidence: 99%

“…As residues in rotational crops cannot be excluded based on these findings, the peer review recommended that rotational crop field trials according to current guidelines should be submitted (see 1.2.2) (EFSA, 2018d).…”

Section: Residues In Plantsmentioning

confidence: 99%

“…The effect of processing on the nature of clopyralid was investigated in the framework of the EU pesticides peer review (EFSA, 2018d).…”

Section: Residues In Plantsmentioning

confidence: 99%

See 4 more Smart Citations

Modification of the existing maximum residue levels for clopyralid in various commodities

Anastassiadou¹,

Bernasconi²,

Brancato³

et al. 2021

EFS2

Self Cite

View full text Add to dashboard Cite

In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant Corteva submitted a request to the competent national authority in Finland to modify the existing maximum residue levels (MRLs) for the active substance clopyralid in various commodities. The data submitted in support of the request were found to be sufficient to derive MRL proposals for wheat, oat and for animal commodities. An adequate analytical method for enforcement is available to control the residues of clopyralid in the plant commodities under consideration at the validated limit of quantification (LOQ) of 0.01 mg/kg. The analytical methods for animal commodities are validated at LOQ of 0.01 mg/kg, but demonstration of extraction efficiency is lacking. Based on the risk assessment results, EFSA concluded that the short-term and long-term intake of residues resulting from the use of clopyralid according to the reported agricultural practices is unlikely to present a risk to consumer health provided that risk mitigation measures are in place to avoid clopyralid residues in rotational and/or succeeding crops.

show abstract

Section: Residues In Plantsmentioning

confidence: 55%

Section: Residues In Plantsmentioning

confidence: 99%

Section: Residues In Plantsmentioning

confidence: 99%

Section: Residues In Plantsmentioning

confidence: 99%

“…The effect of processing on the nature of clopyralid was investigated in the framework of the EU pesticides peer review (EFSA, 2018d).…”

Section: Residues In Plantsmentioning

confidence: 99%

See 3 more Smart Citations

Modification of the existing maximum residue levels for clopyralid in various commodities

Anastassiadou¹,

Bernasconi²,

Brancato³

et al. 2021

EFS2

Self Cite

View full text Add to dashboard Cite

show abstract

Are standard aquatic test species and methods adequate surrogates for use in environmental risk assessment of pesticides in tropical environments?

Santos

Hamer

Tscheschke

et al. 2022

Integr Envir Assess & Manag

View full text Add to dashboard Cite

In regulatory risk assessment, surrogate species of fish, aquatic invertebrates, and primary producers are tested to assess toxicity and subsequently the risk of pesticides to freshwater biota. This study evaluates whether the standard, surrogate test species (mostly temperate in latitudinal distribution) used in many parts of the world are suitable surrogates for first-tier risk assessments involving tropical freshwater biota. Data for the toxicity of pesticides to tropical fish, invertebrates, and primary producer species were extracted from the USEPA ECOTOX database and peer-reviewed literature. For each pesticide, the most sensitive regulatory endpoint extracted from the US Environmental Protection Agency (USEPA) and European Food Safety Authority (EFSA) dossiers for freshwater fish, invertebrates, and primary producers was selected. The ratios of the endpoint for tropical species and for the most sensitive regulatory endpoint for the appropriate taxonomic group were determined. A value >1 indicates that the tropical species is less sensitive than the respective standard regulatory species. Tropical fish species were less sensitive than standard fish species in 84% of the comparisons, and in 93.5% of the comparisons, tropical fish were less or similarly sensitive (within a factor of 5). For aquatic invertebrates, 78.1% of the evaluated tropical species were less sensitive than standard species and 93.3% of tropical invertebrates species were less or similarly sensitive. For primary producers, 96% of tropical species were less sensitive than standard test species. Overall, standard species used globally were more sensitive or similarly sensitive compared to tropical species in more than 93% of the cases. In conclusion, the data show that freshwater toxicity data for pesticides from tests using standard test species, tested according to international accepted guidelines, are appropriate for use in first-tier risk assessments for tropical environments.

show abstract

Reactive oxygen species and depolarization the inner mitochondrial membrane under effect of synthetic auxin herbicides in plant cell culture of Arabidopsis thaliana L.

Fedyaeva,

Lyubushkina,

et al. 2024

Plant Physiol. Rep.

View full text Add to dashboard Cite

Peer review of the pesticide risk assessment of the active substance clopyralid

Cited by 7 publications

References 3 publications

Modification of the existing maximum residue levels for clopyralid in various commodities

Modification of the existing maximum residue levels for clopyralid in various commodities

Are standard aquatic test species and methods adequate surrogates for use in environmental risk assessment of pesticides in tropical environments?

Reactive oxygen species and depolarization the inner mitochondrial membrane under effect of synthetic auxin herbicides in plant cell culture of Arabidopsis thaliana L.

Contact Info

Product

Resources

About