Pemanfaatan bioinformatika dalam bidang pertanian dan kesehatan (The utilization of bioinformatics in the field of agriculture and health)

Parikesit, Arli Aditya; Anurogo, Dito; Putranto, Riza Arief

doi:10.22302/iribb.jur.mp.v85i2.237

Cited by 5 publications

(7 citation statements)

References 71 publications

(82 reference statements)

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“…Massive automation efforts in the field of life sciences will eventually push forward with the inevitable integration with formal sciences, namely with both computer science and data science [78]. In this end, Bioinformatics will play important role to manage the experimental data from the life sciences lab [79]. For instance, utilization of the SUPERFAMILY and Gene Ontology database for annotating the protein domain expression of the Plasmodium sp.…”

Section: Discussionmentioning

confidence: 99%

Introductory Chapter: The Emerging Corner of the Omics Studies for Rational Drug Design

Parikesit¹

2021

Drug Design - Novel Advances in the Omics Field and Applications

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Section: Discussionmentioning

confidence: 99%

Introductory Chapter: The Emerging Corner of the Omics Studies for Rational Drug Design

Parikesit¹

2021

Drug Design - Novel Advances in the Omics Field and Applications

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“…Bioinformatika adalah ilmu yang berbasis multidisipliner yang menggabungkan pendekatan biologi molekuler dan teknik informatika [22]. Sejak kebangkitan dunia internet dimulai pada tahun 1990an berbagai penelitian dilakukan dan perkembangan web membuka tantangan baru terhadap studi-studi penting terkait dataset dan bioinformatika salah satunya didunia adalah sequence nucleotide database yang telah tersedia didatabase pada tahun 1993 [23].…”

Section: Bioinformatikaunclassified

Penerapan Extreme Programming dalam Pengembangan Fitur Interoperabilitas Pada Aplikasi Bioinformatika

Hadinata

Sinaga

2022

mib

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Extreme Programming or XP Model is an application development framework used to create applications that require rapid adaptation. Even in the condition that the application is still in use, the use of this development model is quite appropriate if it is applied to the development of Several features of Bioinformatics Applications. The widespread use of interoperability features found in many applications has made it easier for many system developers to develop applications on various system devices. Likewise, bioinformatics applications that carry out various in silico studies. Application development using the XP Model for special applications that are rarely used for feature additions, the difficulty is implementing rapid adaptation to interoperability feature development without design and analysis of specific applications. The contribution of this paper is to make notes and blueprints for adding interoperability features for bioinformatics applications. Besides that, the XP model is a different method when used to carry out the application development process, especially if it is used to add features to special applications. The success obtained in the development of this application cannot be separated from the advantages of the XP model itself, because the XP model can be implemented in conditions of lack of human resources and the possibility of applying practical principles and techniques in the process. As a result, development is carried out quickly and the application runs well through testing results and then applications can be used to perform processes in silico through interaction between applications to applications to the dataset provider.

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“…Berbagai senyawa metabolit sekunder pada anggrek yang telah diteliti, tersedia pada website resmi yang berfungsi sebagai basis data internasional. Basis data ini berfungsi sebagai penyedia objek penelitian, menjaga akurasi penelitian, serta meningkatkan prediksi data yang presisi (Parikesit et al, 2017).…”

Section: Pendahuluanunclassified

“…Studi in silico diprediksikan akan terus meningkat karena dari segi biaya relatif terjangkau (Parikesit et al, 2017). Studi in silico juga dapat dimanfaatkan dalam pembuatan desain obat, mengetahui interaksi antar protein yang dapat menyebabkan suatu penyakit, analisis ekspresi genetik hingga penanda molekuler (Parikesit et al, 2017).…”

Section: Pendahuluanunclassified

Potential of Orchids Secondary Metabolites as Anti-Cancer and Antimicrobial Based on Prediction of Phytochemical Activity with Online PASS-Software

Yasmin

Mafiroh

Kinasih

et al. 2022

AMS

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Abstract Orchidology is part of the branch of botany, it deals with a large family of monocotyledonous plants, Orchidaceae. Orchids have been used as traditional herbal medicines in Indonesia which are believed to be antimicrobial and anti-cancer. Orchids are able to produce secondary metabolites as their protective agent due to the extreme environment. Orchids have great diversity and potential to be the object of research, not only in experimental studies but also in a computational studies like in silico. Nowadays, molecular or metabolite data are available on the official-standard website as an international database. This study was conducted by analyzing web-based data to provide information about the potential of orchids that have been trusted as herbal medicines. In this study, secondary metabolite from Vanilla spp., Dendrobium spp., and Vanda spp., were selected in the existing literature as antimicrobial and anti-cancer drugs. Secondary metabolites obtained from the KNApSAck-3D core system and Phytochemical and Prediction of Substance Activity Spectrum (PASS) were performed to determine the potential anti-cancer and antimicrobial activity. Based on in silico analysis through PASS online, the secondary metabolites of orchids that have potential as antimicrobials in this study were Dendroside E and Dendromonilised D from Dendrobium also Parviflorin, Licoisoflavone and Luteine extracted from Vanda spp. The secondary metabolite of Vanilla planifolia which has potential as anti-cancer for further research is 4-Hydroxybenzoic acid as a Chlordecone reductase inhibitor extracted from shoots. Keywords: orchid, antimicrobial, anticancer, secondary metabolite, PASS online

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Pemanfaatan bioinformatika dalam bidang pertanian dan kesehatan (The utilization of bioinformatics in the field of agriculture and health)

Abstract: Bioinformatics can be used to manage the data storage resulted from in silico molecular biology experiments. Off-network (offline)

Cited by 5 publications

References 71 publications

Introductory Chapter: The Emerging Corner of the Omics Studies for Rational Drug Design

Introductory Chapter: The Emerging Corner of the Omics Studies for Rational Drug Design

Penerapan Extreme Programming dalam Pengembangan Fitur Interoperabilitas Pada Aplikasi Bioinformatika

Potential of Orchids Secondary Metabolites as Anti-Cancer and Antimicrobial Based on Prediction of Phytochemical Activity with Online PASS-Software

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