Plans for the development of nuclear power plants in Indonesia have existed since the Soekarno regime in 1945, but have never reached the policy implementation stage until the current presidency of Joko Widodo. This is related to obstacles that can be in the form of Threats, Disruptions, Obstacles and Challenges (AGHT), so that it always fails in the implementation process, both on a global, national and regional scale due to issues in the social, political, technological, and other realms. The purpose of this study is to analyze the scenario of Threats and Disruptions mitigation scenarios for the development of nuclear power plants in Indonesia. The results of the study indicate that the mitigation of the threat of nuclear power plant development plans in Indonesia is through First Track Diplomacy and Second Track Diplomacy, guided by Law No. 10 of 1997 in decision making, and integrated community involvement in supporting government programs. Mitigation of disruptions to the nuclear power plant development plan in Indonesia through a policy of targeting the energy mix by optimizing the use of NRE other than nuclear, while developing a nuclear power plant development plan, implementing a Carbon Tax, socialization through K/L cooperation regarding the use of nuclear energy for nuclear power plants, various fields and second track diplomacy.