Pemoline poisoning

David, Timothy; Vale, Allister

doi:10.1007/bf00310489

Cited by 7 publications

(4 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Only symmetric observables, which are invariant under all the continuous symmetries, can have a non-zero value. There are theorems [38][39][40] that guarantee the IR-finiteness of the symmetric observables.…”

Section: Infra-red Divergences Of the Critical Theorymentioning

confidence: 99%

See 1 more Smart Citation

The standard model from a new phase transition on the lattice

Shamir

1998

Phys. Rev. D

View full text Add to dashboard Cite

Several years ago it was conjectured in the so-called Roma Approach [1], that gauge fixing is an essential ingredient in the lattice formulation of chiral gauge theories. In this paper we discuss in detail how the gauge-fixing approach may be realized. As in the usual (gauge invariant) lattice formulation, the continuum limit corresponds to a gaussian fixed point, that now controls both the transversal and the longitudinal modes of the gauge field. A key role is played by a new phase transition separating a conventional Higgs or Higgs-confinement phase, from a phase with broken rotational invariance. In the continuum limit we expect to find a scaling region, where the lattice correlators reproduce the euclidean correlation functions of the target (chiral) gauge theory, in the corresponding continuum gauge.11.15.Ha 12.15.-y 11.30.Rd

show abstract

Section: Infra-red Divergences Of the Critical Theorymentioning

confidence: 99%

“…The theorems on the finiteness of symmetric observables, in particular ref. [40], generalize to four dimensions. Also, as in two dimensions, the predictions of the weak-coupling expansion are often valid, if interpreted carefully [41].…”

Section: Infra-red Divergences Of the Critical Theorymentioning

confidence: 99%

The standard model from a new phase transition on the lattice

Shamir

1998

Phys. Rev. D

View full text Add to dashboard Cite

show abstract

“…This property was exploited in Refs. [30][31][32] in the context of dimensional regularization, and was given a rigorous proof to all orders of perturbation theory by David [33][34][35]. Three-loop calculations for the renormalization-group functions were first presented by Hikami and Brezin [36] for O(N) models, and by Hikami [37] for CP N −1 models.…”

Section: Spin Models In D Dimensions and Renormalizabilitymentioning

confidence: 99%

The 1/N expansion of two-dimensional spin models

Campostrini

Rossi

1994

Nuclear Physics B - Proceedings Supplements

View full text Add to dashboard Cite

A short review of all available results (perturbative, nonperturbative, and exact) on d-dimensional spin models is presented in order to introduce the discussion of their 1/N expansion at d = 2, where the models are asymptotically free.A general two-dimensional spin model with U(N ) invariance, interpolating between CP N −1 and O(2N ) models, is studied in detail in order to illustrate both the general features of the 1/N expansion on the lattice and the specific techniques devised to extract scaling (field-theoretical) behavior.The continuum version of the model is carefully analyzed deriving quantitative O(1/N ) physical predictions in order to establish a benchmark for lattice computations.The 1/N expansion on the lattice, including second-nearest-neighbor interactions, is set up by constructing explicitly effective propagators and vertices, and exhibiting a number of exact results and integral representations that allow a substantial reduction of the numerical effort. The technique of asymptotic expansion of the lattice propagators, basic to the derivation of analytical results in the scaling domain, is presented in full detail and applied to the model. Physical quantities, like the free energy and different definitions of correlation length, are evaluated.The lattice renormalization-group trajectories are identified and universality among different lattice (and continuum) schemes in the scaling region is explicitly proven. As a byproduct, representations of the O(1/N ) contribution to the Λ-parameter ratios and to the lattice β functions are obtained.A review of other developments based on the lattice 1/N expansion (finite size scaling, higher orders, fermionic models) is presented.

show abstract

“…One of our patients (case 4) experienced a mild elevation of serum AST, LDH, and CPK, which may be suggestive of pemoline-induced hepatotoxicity. Except for the patient who experienced hypertension lasting 4 days and a seizure 5 days after ingestion, 22 symptoms associated with pemoline overdose appear to abate within 48 to 72 hours.…”

Section: Discussionmentioning

confidence: 97%

Pemoline Ingestion in Children: A Report of Five Cases and Review of the Literature

Nakamura

Blumer

Reed

2002

The Journal of Clinical Pharma

View full text Add to dashboard Cite

The authors describe five pediatric cases of excessive pemoline ingestion. Based on their experience compared with previously reported cases in the literature, they describe the clinical presentation and rational treatment recommendations for acute pemoline ingestion. Overall, patients experienced a relatively benign clinical course following pemoline ingestion. Symptoms of pemoline ingestion appear to be primarily an accentuation of the drug's pharmacological effects on the central nervous and cardiovascular systems with sinus tachycardia, hypertension, hyperactivity, choreoathetoid movements, and hallucinations being most commonly observed. These findings are consistent with previously reported cases. Possible rhabdomyolysis manifested by evaluation of serum CPK was also observed in 3 of 4 patients in whom this laboratory parameter was measured and appears to be a common finding in acute pemoline poisoning. After acute ingestion, symptoms occurred within 6 hours, lasting up to 48 hours in all patients. Gastric lavage and/or activated charcoal would be effective decontamination measures, whereas ipecac-induced emesis should be avoided after massive ingestion due to the possibility of seizures. Aggressive use of a benzodiazepine appears a reasonable first choice to treat associated involuntary movements, tremor, hyperactivity, irritability, and agitation. Phenothiazines or butyrophenones may also be used especially for serious life-threatening symptoms, including hypertensive crisis and severe hyperthermia, although these serious complications of stimulant overdose have not been reported after pemoline ingestion. If a patient should experience pemoline-induced hypertensive crisis, individual dose titration of labetalol or sodium nitroprusside would appear reasonable pharmacologic approaches for rapid stabilization of blood pressure.

show abstract

Pemoline poisoning

Cited by 7 publications

References 6 publications

The standard model from a new phase transition on the lattice

The standard model from a new phase transition on the lattice

The 1/N expansion of two-dimensional spin models

Pemoline Ingestion in Children: A Report of Five Cases and Review of the Literature

Contact Info

Product

Resources

About