Penfigoide ampolloso en lactante tras vacunación

Postvaccination Bullous Pemphigoid in Infancy: Report of Three New Cases and Literature Review

“…The outcome was favorable in all patients, with resolution of lesions in 2 to 6 months. Three cases showed recurrence with subsequent vaccinations, although less severe than the initial outbreak , so the authors did not consider it necessary to avoid subsequent vaccinations. The etiology is uncertain.…”

“…Therapy is based on systemic steroids at doses ranging from 1 to 2 mg/kg/day of prednisone . There have been some 100 reported cases of childhood BP , of which 18 cases have been related to vaccine administration, of which only 9 cases occurred in infants younger than 6 months of age (Table ). The latency period ranged between a few hours and 3 weeks.…”

“…All cases had palmoplantar involvement, and mucosal membranes were spared in all but one case. The tetanus, diphtheria, pertussis, and polio vaccine was administered in all cases , although in some patients, vaccinations against pneumococcus , H. influenzae B , hepatitis B , and meningococcus were also administered and cannot be excluded as triggering factors. Systemic steroid treatment was successful in all but one case, in which high‐potency topical steroids achieved resolution.…”