2018
DOI: 10.31596/cjp.v2i2.23
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PENGARUH EKSTRAK ETANOL RANTING BUAH PARIJOTO (Medinilla speciosa Blume) TERHADAP KADAR GLUKOSA DARAH TIKUS PUTIH DENGAN METODE INDUKSI ALOKSAN

Abstract: Pada tahun 2000 di Indonesia terdapat 8,4 juta pengidap penyakit diabetes mellitus dan diperkirakan akan menjadi 21,3 juta pada tahun 2030 (Soegondo dkk, 2009). Indonesia merupakan negara dengan kekayaan alam yang besarsebagai aset negara yang perlu digali sehingga dapat dimanfaatkan secara optimal. Salah satu kearifan lokal, di desa Colo dilereng Gunung Muria, Kabupaten Kudus, Jawa Tengah yaitu parijoto (Medinilla speciosa Blume). Tanaman yang mengandung tanin, Flavonoid, Saponin dan glikosida dalam buahnya, … Show more

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Cited by 5 publications
(8 citation statements)
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“…Parijoto fruit extract (Medinilla speciosa Blume) was prepared by maceration method using 70% ethanol solvent for 24 hours then filtered using filter paper. The extract was evaporated in a rotatory evaporator at 70˚C to separate 70% ethanol solvent from the extract (Kurniawati 2015;Legawati et al 2020) The remaining filtrate was followed by evaporation using a waterbath at a temperature of 70˚C. The weight of parijoto fruit extract obtained was 12 g and the yield was 1.5% of the total extracted sample.…”
Section: Methodsmentioning
confidence: 99%
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“…Parijoto fruit extract (Medinilla speciosa Blume) was prepared by maceration method using 70% ethanol solvent for 24 hours then filtered using filter paper. The extract was evaporated in a rotatory evaporator at 70˚C to separate 70% ethanol solvent from the extract (Kurniawati 2015;Legawati et al 2020) The remaining filtrate was followed by evaporation using a waterbath at a temperature of 70˚C. The weight of parijoto fruit extract obtained was 12 g and the yield was 1.5% of the total extracted sample.…”
Section: Methodsmentioning
confidence: 99%
“…Doses were modified from prior research on parijoto fruit on liver rats with a dose modification close to 90 mg/200 g BW. Each extract was dissolved in 0.5% CMC-Na gradually until a suspension was formed and the volume was made up to 35 ml (Kurniawati 2015;Legawati et al 2020).The extract was administered orally to mice using oral gavage, 1 ml each mice, expressed as mg/20 g of body weight for 56 days.…”
Section: Parijoto Fruit Extract In Fatty Livermentioning
confidence: 99%
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“…Menambah ekstrak kental dengan asam asetat dan H2SO4, kemudian dipanaskan. Apabila tidak mengandung etanol maka tidak tercium bau ester (etil asetat) (Kurniawati, 2015).…”
Section: Uji Bebas Alkohol Ekstrak Etanol Daun Palaunclassified
“…Induksi kuning telur merupakan induksi secara eksogen, yang dipilih supaya mirip dengan yang dialami oleh penderita hiperlipidemia yang disebabkan karena pola makan yang tidak sehat, dengan mengkonsumsi makanan tinggi lemak. Induksi kuning telur juga mudah dan harganya terjangkau (Kurniawati, 2015).…”
Section: Induksi Kuning Telurunclassified