Pengaruh Metode Pengeringan Terhadap Aktivitas Antioksidan Ekstrak Etanol

Abstract

Drying is the most important step to keep the compound stability in simplicia and is very influential to produce good quality igredients in the antioxidant activity contained in the simplicia. Antioxidants are oxidation-free inhibitors of free radical reactions. Parijoto is one of the plants that have antioxidant compounds.This study aims to determine the effect of drying, concentration of antioxidant activity of parijoto (Medinilla speciosa Blume) fruit. The drying method used is direct sunlight drying, indirect sunlight and oven. The antioxidant activity of ethanol extract on drying method was determined by 2,2 diphenyl-1-picrylhidrazyl (DPPH) method which is free radical. The qualitative test DPPH showed that the higher levels of ethanol extract from the three drying methods further diminished the color of DPPH solution in ethanol.The result showed thet the drying method gave different effect to the antioxidant activity of parijoto fruit which is significant(p0,05). Drying methods wich have high antioxidant activity are given by drying using oven method with an IC50 value 33,75µg/ml.

Potential Antioxidant Activity Methods DPPH, ABTS, FRAP, Total Phenol and Total Flavonoid Levels of Macaranga hypoleuca (Reichb. f. & Zoll.) Leaves Extract and Fractions

“…Table 1 shows that the yield of methanol extract from M.hypoleuca leaves is 10%, indicating that there are many secondary metabolite compounds contained in the leaves. Methanol was used as a solvent for the maceration process because it can extract both non-polar and polar active compounds [28], and is known to be a better solvent than others [20]. The extract is then fractionated using n-hexane, ethyl acetate, butanol, and water.…”

Penetapan Kadar Fenolik dan Flavonoid Total Ekstrak Etanol Buah Parijoto (Medinilla speciosa Blume) dengan Metode Spektrofotometri UV-Vis

“…Ekstrak etanol dari buah parijoto diketahui mengandung flavonoid yang berperan dalam penurunan kadar gula dalam darah (Vifta & Advistasari, 2018). Ekstrak etanol buah parijoto juga diketahui memiliki aktivitas sebagai antioksidan (Pujiastuti & Saputri, 2019;Vifta et al, 2019). Selain itu, ekstrak etanol buah parijoto juga memiliki aktivitas sebagai antikanker pada sel kanker payudara (T47D) (Tusanti et al, 2014).…”

Effect of Drying Method on Levels of Antioxidant Activity, Total Flavonoid Levels, and Total Phenol Levels in Ethanol Extract of Bawang Dayak (Eleutherine americana) Leaves

“…Temperature also affects the drying process. The temperature in the sun is not as big as the temperature in the oven which uses a temperature of 50 o C. Increase temperature can cause a decrease in the total phenolic concentration in the sample (Pujiastuti & Saputri, 2019).…”

“…The drying process is one of the stages in the manufacture of Simplicia which can affect the good quality of the material in terms of the antioxidant activity contained in the simplicial material (Pujiastuti, 2019). Drying methods can be done in various ways including drying in the sun and using an oven.…”