One of the challenges of education today is building 21st century skills. The purpose of this research is to find out the development of interactive e-modules using the Canva application for second semester students at PGRI Silampari University which was developed from valid and practical aspects. The research method is using the Research and Development (R&D) method. The design and development of this learning media uses a 4-D development model which generally consists of 4 stages, namely defining, designing, developing, and disseminating. Based on the research results, the development of interactive e-modules using the Canva application is valid and practical. This is from the results of expert validation of materials, construction/media and language, obtained an average score of 4.28, 4.40 and 4.40 with a very valid category. Furthermore, the results of the practicality of 7 students showed an average score of 4.67 with a very practical category.