Based on the previous research, the result of the learning process of Biology education STKIP PuangrimaggalatungSengkang in many subjects still include at a low level. The low learning outcome is shown from there are some students are difficult to comprehend and analyze the learning materials.Abstract: The objective of the research is to analyze the scientific literacy initial ability of biology education students in PRIMA Sengkang. The kind of research is descriptive-qualitative. This research was done in STKIP PRIMA Sengkang University in 2018/2019 academic year. The subject of the research was all the students of Biology education, specifically Anatomy and Physiology subject. The qualitative data of this study were collected through a written test then it was analyzed by using the qualitative-descriptive method. The result of the study showed that the students' scientific ability in Biology Education prima Sengkang was at a low level. The use of scope management of the given subject can be applied to overcome the students' low ability of scientific literacy.