Atopic dermatitis also known as atopic eczema or eczema can attach to individuals into adulthood or even in adulthood. Atopic dermatitis can influence psychological well-being aspects because it is closely related with the selfacceptance of atopic sufferers, positive relationship with others, environmental mastery, life goals, and personal growth of atopic sufferers with all the dynamics. This study aims to determine the psychological well-being of the current subjects, who has had atopic dermatitis since childhood. This study takes a qualitative approach and uses the case study method. This study chose GP and UN as subjects with qualifications both are sufferers of atopic dermatitis since childhood. The data sources used are primary and secondary data. This study obtained primary data from three informants: the sufferer, their mother, and friends. The secondary data consists of previous studies, literature reviews, books, journals, and other sources. The data obtained were then analyzed using a descriptive analytic method, with the dimension of psychological well-being as the theoretical foundation. Based on the data findings, it was determined that the two subjects had similar psychological well-being when they suffer atopic dermatitis. Both subjects have reached a state of psychological well-being. Despite in comparison to GP, UN does not provide adequate emotional control.