The liquid waste of the tofu industry contains high organic contaminants, such as proteins and amino acids. These organic compounds causes liquid waste of tofu industry to contain high BOD, COD, and TSS so that it can pollute the environment. Therefore, tofu liquid should be removed first by electrocoagulation method. This method has the potential to purify tofu liquid waste and decrease the content of COD, BOD, TSS, and pH contained without the addition of coagulants. The purpose of this study was to determine the effect of voltage and flow rate to neutralize pH, and reduce levels of COD, BOD, and TSS in tofu liquid waste. The parameters tested included COD, BOD, TSS, and pH. The electrocoagulation process uses electrical power that flows in the direction of the electrode. The electrocoagulation reactor was paired with a cable connected to the power supply then connected to an electric current with voltage and flow rate variations. The results of this study found that optimum conditions were obtained at current of 12 V and flow rate of 0.087 L/min with increasing pH from pH from 3.5 to 6.7, percent removal of COD 72.17%, percent removal BOD 71.53% , and percent removal TSS 90.90%.