Penicillin-Resistant Streptococcus constellatus as a Cause of Endocarditis

Levin, Robert M.; Pulliam, Lynn; Mondry, Carol; Levy, Donna E.; Hadley, W K; Grossman, Moses

doi:10.1001/archpedi.1982.03970370044011

Cited by 8 publications

(5 citation statements)

References 26 publications

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“…Murray et al 7also point out that species identification is important because S. milleri (intermedius) may be associated with serious suppurative infections. Identification and susceptibility testing may be more important in the future because of the emergence of penicillin-resistant organisms (6). We have found that species identification of alphahemolytic streptococci isolated from cerebrospinal fluid is useful in distinguishing clinically significant isolates from those considered to be contaminants, such as S. mitis (unpublished data).…”

Section: Discussionmentioning

confidence: 96%

“…The development of rapid methods for species identification of alpha-hemolytic streptococci would be of great value in clinical microbiology. This not only would provide rapid results, but also would provide the clinician with more spe-cific information on which to base initial therapeutic decisions, especially in light of a recent report of a penicillin-resistant alpha-hemolytic streptococcus (6). Recently, a new 4-h system for the identification of streptococci became available (API 20S; Analytab Products [API], Plainview, N.Y.).…”

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confidence: 99%

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Evaluation of a rapid system for species identification of alpha-hemolytic streptococci

Nachamkin¹,

Lynch²,

Dalton³

1982

J Clin Microbiol

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A new 4-h commercial system (API 20S; Analytab Products, Plainview, N.Y.) for the identification of streptococci was compared with the conventional biochemical profile method in the species identification of alpha-hemolytic streptococci. A total of 194 clinical isolates (including 74 isolated from blood cultures, 64 isolated from wound cultures, and 56 isolated from respiratory cultures) and 20 reference strains were tested. Only 4 of the 20 reference strains were correctly identified to species level by the API 20S system. Six were identified to group level (viridans), four were incorrectly identified, and six did not conform to the identification key. Of the 194 clinical isolates tested, 79 (39%) were correctly identified to species level, 34 (17.5%) were identified to group level, 34 (17.5%) were incorrectly identified, and 50 (25.8%) did not conform to the identification key. Of the 12 different species of alpha-hemolytic streptococci isolated from clinical specimens, the API 20S system consistently identified Streptococcus faecalis and Streptococcus faecium, but consistently misidentified the other 10 species, especially Streptococcus mitis. Our results indicate that for identification to species level, the API 20S system is of little value for alpha-hemolytic streptococci other than enterococci.

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Section: Discussionmentioning

confidence: 96%

mentioning

confidence: 99%

Evaluation of a rapid system for species identification of alpha-hemolytic streptococci

Nachamkin¹,

Lynch²,

Dalton³

1982

J Clin Microbiol

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“…These organisms are usually sensitive to βlactam antibiotics, such as penicillin, ceftriaxone and ampicillin, doxycycline, erythromycin, vancomycin, and the aminoglycosides, and intermediately sensitive to clindamycin. Increased resistance to penicillin and clindamycin has been described [12,14,15]. S. constellatus causes superficial abscesses often isolated with anaerobic bacteria [16].…”

Section: Discussionmentioning

confidence: 99%

Streptococcus constellatusand Prevotella bivia Penile Abscess

Nalmas

Bishburg

Chan

2007

The Scientific World JOURNAL

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“…Only 10 cases are reported in the literature [5][6][7][8][9][10][11][12][13][14]. It is reported that S. constellatus is not readily associated with the heart valves, which may explain why S. constellatus rarely causes IE [15,16].…”

Section: Discussionmentioning

confidence: 99%

“…However, 1 group of S. viridans, the S. milleri group, which includes S. constellatus, S. anginosus, and S. intermedius, rarely cause IE; among these, S. anginosus is predominant [4]. S. constellatus is a very rare pathogen of IE; there are only 10 case reports in the literature [5][6][7][8][9][10][11][12][13][14]. The clinical features of IE due to S. constellatus remain unclear.…”

Section: Introductionmentioning

confidence: 99%

Infective endocarditis due to a rare pathogen, Streptococcus constellatus, in a patient with gingivitis: A case report and review of the literature

et al. 2013

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AbstractA 78-year-old Japanese man with a 5-day history of fever (∼38°C) and decreased appetite was admitted to our hospital. Transesophageal echocardiography revealed aortic valve vegetation. Streptococcus constellatus was detected from a blood culture. An antibiotic sensitive to this strain was administered for 6 weeks, and the patient has been well for 6 months without any sign of relapse. A review of all documented cases of infective endocarditis due to S. constellatus revealed nonspecific initial symptoms, especially coughing, and complications of abscess formation and septic embolisation. Clinicians should carefully consider the choice of antibiotic agents in the treatment of infective endocarditis due to S. constellatus, because penicillin-resistant strains have been documented in some cases.

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Penicillin-Resistant Streptococcus constellatus as a Cause of Endocarditis

Cited by 8 publications

References 26 publications

Evaluation of a rapid system for species identification of alpha-hemolytic streptococci

Evaluation of a rapid system for species identification of alpha-hemolytic streptococci

Streptococcus constellatusand Prevotella bivia Penile Abscess

Infective endocarditis due to a rare pathogen, Streptococcus constellatus, in a patient with gingivitis: A case report and review of the literature

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