Penile Cancer—Prevention and Premalignant Conditions

Profile of Patients with Penile Neoplasms Who Have Undergone Penectomy

“…The prevalence of phimosis among patients with this type of cancer has already been described [24,31], it is 74%, and on the other hand it has been found that, in countries where neonatal circumcision is practiced, such as Israel and the USA, the occurrence of penile cancer was extremely low, with rates < 1%. Phimosis can determine the retention of smegma [27], favoring the conditions of chronic irritation with or without bacterial inflammation of the foreskin and glans, which may represent a critical component in tumor development and progression.…”

“…On the other hand, the fight against smoking must be strongly advised through public health programs [24].…”

Squamous cell carcinoma of the penis: therapeutic targeting of the epidermal growth factor receptor

“…In addition to this, human papillomavirus (HPV) has been shown to have a central role in tumorogenesis [1]. HPV DNA can be identified in up to 80% of tumour specimens.…”

“…In the current issue of BJUI Danuser et al [1] present their prospective randomised single-centre study evaluating the effectiveness of 1-week vs the more traditional 4-week ureteric stent placement, after either a laparoscopic (LPP) or robot-assisted laparoscopic pyeloplasty procedure (RALPP) for PUJO.…”

Human Papillomavirus and Related Diseases - From Bench to Bedside - A Clinical Perspective

“…The wide variation of penile SCC prevalence is likely explained by the large variance in risk factors, in particular, the practice of neonatal circumcision (Minhas et al, 2010). The incidence is very low among Jewish populations that commonly practice neonatal circumcision (0.1 per 100,000) [Morris et al, 2011;Pow-Sang et al, 2010].…”