Penile pyoderma gangrenosum

Abstract

A 70-year-old man presented with indurated penile ulcers of 1-month duration. Initial biopsy was reported as chronic ulcer. A repeat biopsy done due to inadequate response to doxycycline showed features of pyoderma gangrenosum. The ulcer healed with a course of steroids and has not recurred till date.

Granulomatous pyoderma gangrenosum of the genitalia in the absence of Crohn′s disease

“…[1] PG is, usually, seen over the trunk and lower extremities, but solitary lesion over the genitalia is uncommon. [23] PG lesions on histopathology may show granulomatous foci when it is associated with inflammatory bowel disease, especially Crohn's disease. [4] Other uncommon variants of PG are pustular PG, bullous PG, and vegetative PG.…”

Pyoderma gangrenosum masquerading as Donovanosis

“…[89] Donovanosis was the most probable differential diagnosis because it presents with ulceration over genitalia with rare features of granulation in groin and flexures of varying duration. But the absence of Donovan bodies and histopatholoical features of PG ruled out Donovanosis.…”

Broadening the differential: A case of penile pyoderma gangrenosum

“…Pyoderma gangrenosum (PG) is a noninfectious inflammatory condition characterized by neutrophilic dermatosis. 1 PG most commonly affects the lower extremities, but has also been seen on the face, neck, and rarely in penile skin. 1 PG is a diagnosis of exclusion and can be delayed due to misdiagnosis of malignancy or a sexually transmitted infection that fails to respond to standard therapy.…”

“… 1 PG most commonly affects the lower extremities, but has also been seen on the face, neck, and rarely in penile skin. 1 PG is a diagnosis of exclusion and can be delayed due to misdiagnosis of malignancy or a sexually transmitted infection that fails to respond to standard therapy. 2 It is, however, important to keep PG in the differential diagnosis as serious complications, such as urethral fistulas, have occurred when PG is not diagnosed and managed in a timely manner.…”

“… 2 It is, however, important to keep PG in the differential diagnosis as serious complications, such as urethral fistulas, have occurred when PG is not diagnosed and managed in a timely manner. 1 Treatment of PG is driven by immunosuppressive agents including cyclosporine and corticosteroids. 3 Although PG resolves with appropriate treatment, the rarity and nonspecific presentation of penile PG can lead to mismanagement and extension of the lesion.…”