The success of the intensive culture of Sangkuriang catfish (Clarias gariepinus var. Sangkuriang) highly depends on the availability of feed. The feed is the most significant share of cost production hamper (50-60%). Therefore, it is suggested that feed utilization is inefficient. One of the solutions is to enrich the commercial feed with yeast (Saccharomyces cerevisiae). The research aimed to identify the impacts of yeast (S. cerevisiae) enhanced feed on feed efficiency, growth, and survival rate of Sangkuriang catfish fingerlings. The treatments research was yeast (S. cerevisiae) enrichment in the commercial feed at the various dosages: 0 %/kg feed (A), 3 %/kg feed (B), 6 %/kg feed (C), 9 %/kg feed (D), and 12 %/kg feed (E). The yeast (S. cerevisiae) enrichment in the commercial feed increased feed efficiency and survival rate of Sangkuriang catfish fingerlings. The optimum dosage of S. cerevisiae for apparent digestibility coefficients for protein (ADCp), efficiency feed utilization (EFU), protein efficiency ratio (PER), and relative growth rate (RGR) ranged from 6.10% to 6.51%/kg feed.