“…In one study (Hamilton et al, 1967b), the soporific effect of pentazocine given pre-operatively (20, 30,40 and 60 mg) increased with dosage, but even at 60 mg was slightly less than that following morphine 10 mg or pethidine 100 mg. Although a high proportion of patients become drowsy or go to sleep after a therapeutic injection of pentazocine, many authors have commented upon the fact that sleeping patients were easily aroused (Gaines, 1967;Finestone and Katz, 1966) and that when aroused were alert and cooperation (Wilson, 1971).…”