“…Recent reviews of the literature by Sandweiss et al (1939), Bralow et al (1948), and Sandweiss (1951) make it clear that despite much research there is no clear proof of a relationship between the sex hormones and peptic ulcer. Certainly the use of these hormones in the treatment of ulcer has been disappointing, though it should be observed that they are present in pregnancy in much larger amount than can be given therapeutically.…”