Perbandingan Antioksidan Ekstrak Etanol Daun Gaharu (Aqularia malaccensis L.) dan Ketiga Fraksi Berbagai Pelarut (Heksan, Etil Asetat, dan Air)

Abstract

The research comparison of antioxidant activity extracts and various fractions of Aquilaria malaccensis L. leaves had been done. Extraction had been done by maceration method of 350 grams of leaf powder used ethanol 70% solvent for 3 days to 5 repetitions, then fractionation used hexane, ethyl acetate and akuades solvents. The extraction yield obtained 3.57 (%w/w) viscous extract yield, while the fractionation results obtained hexane, ethyl acetate and water fractions were 43.14, 32.67, and 22.20 (%w/w). Antioxidant test was carried out used DPPH (diphenyl-picrylhydrazyl) method, where the inhibitory value of DPPH (% inhibition) was tested at various concentrations of sample test solutions, for thick extracts at concentrations of 80; 60; 40; 20; and 10 ppm, and fraction samples at concentrations 200; 160; 120; 80; and 40 ppm. IC50 calculation results showed that antioxidant activity was classified as very strong in thick extracts and ethyl acetate fraction, were 16.45 and 47.69 ppm, and strong antioxidants were found in n-hexane fraction and water fraction were 57.24 and 76.95 ppm.

Formulasi dan Evaluasi Gel Pelembap Ekstrak Mesokarp Semangka [Citrullus lanatus (Thunb.) Matsum. & Nakai] sebagai Antioksidan

“…Aktivitas antioksidan yang diberikan salah satunya berasal dari senyawa flavonoid. Pada senyawa flavonoid terdapat gugus hidroksil bebas yang memiliki kemampuan untuk menangkal radikal bebas melalui pemutusan reaksi berantai dan berubah menjadi senyawa yang lebih stabil (Hasanah et al, 2020). Semakin besar konsentrasinya zat aktif dalam formulasi maka semakin kecil nilai IC50 sehingga aktivitas antioksidannya semakin tinggi.…”

Antioxidants and chemical compounds of hot water extract agarwood leaves Wikstroemia tenuiramis Miq

“…The results of the phytochemical test of the aqueous fraction of the thick extract of agarwood leaves contain flavonoid, phenolic and triterpenoid compounds and their antioxidant activity is 76,95 μg/ml [7]. The aqueous agarwood leaf extract has antioxidant activity [8].…”