Perbandingan Levofloxacin dengan Ciprofloxacin Peroral dalam Menurunkan Leukosituria Sebagai Profilaksis Isk pada Kateterisasi di RSUP. Dr. M. Djamil Padang

Sofyan, Marwazi; Alvarino, Alvarino; Erkadius, Erkadius

doi:10.25077/jka.v3i1.29

Cited by 2 publications

(5 citation statements)

References 4 publications

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“…It has low resistance bacteria to more antibiotics compared to group fluoroquinolones and others. The results of other studies show that about 2030% of bacteria cause infection channel urinary resistance against class antibiotics fluoroquinolones, especially ciprofloxacin (Sofyan et al 2014;Adil dan Kundarto 2019).…”

Section: Ijssr Page 2500mentioning

confidence: 99%

“…Levofloxacin is antibiotics spectrum wide group fluoroquinolones generation third with more activity Good to gram positive bacteria and have level resistance bacteria to more antibiotics low compared to group fluoroquinolones others , p This because Lots study show that as many as 2030% Bacteria reason infection channel urinary resistant to antibiotics group fluoroquinolones, especially ciprofloxacin (Sofyan et al 2014;Adil dan Kundarto 2019).…”

Section: Ijssr Page 2500mentioning

confidence: 99%

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Quantitative Study Of Antibiotic Use In Patients With Urinary Tract Infections At Rsu X In East Jakarta 2019

Hasan,

Yardi,

Amalia

2023

IJSSR

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Urinary tract infection is a health problem that can increase morbidity and even increase the death rate both in Indonesia and in the world. Urinary tract infection is the second most common infectious disease after upper respiratory tract infection which in its treatment must use antibiotic therapy, so the treatment must be appropriate and rational. The purpose of this study was to determine the use of antibiotics quantitatively using the ATC/DDD and 90% DU methods in patients with urinary tract infections at RSU X in East Jakarta. Methods, This research is a descriptive study using a crosssectional design. Data collection was carried out retrospectively through the medical records of urinary tract infection patients at RSU the inclusion and exclusion criteria. The results showed that the total DDD/100 patientdays in this study was 96.65% with the highest type of antibiotic, namely levofloxacin, 44.07% DDD/100 patientdays. Drugs included in the DU segment 90% were levofloxacin (45.60%), ceftriaxone (21.54%), cefoperazone (11.33%), and amoxicillin clavulanate (9.00%). Keywords: Antibiotics, urinary tract infection, ATC/DDD, 90% DU.

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Section: Ijssr Page 2500mentioning

confidence: 99%

Section: Ijssr Page 2500mentioning

confidence: 99%

Quantitative Study Of Antibiotic Use In Patients With Urinary Tract Infections At Rsu X In East Jakarta 2019

Hasan,

Yardi,

Amalia

2023

IJSSR

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“…Infeksi saluran kemih (ISK) adalah keadaan dimana kuman tumbuh dan berkembang biak dalam saluran kemih dalam jumlah yang bermakna. Diagnosa ISK ditegakkan berdasarkan manifestasi klinis dengan bakteriuria dan leukosituria (bermakna: ≥ 10 / LPB atau pyuria) [1]. ISK dapat berlangsung dengan gejala simptomatis (dysuria, nyeri supra pubis, demam, nyeri pada daerah pinggang) atau tanpa gejala/asimptomatis [1,2].…”

Section: Pendahuluanunclassified

“…Keberhasilan terapi dinilai dengan berkurangnya gejala ISK simptomatis pada saat pasien masuk rumah sakit dan setelah mendapatkan terapi antibiotik selama > 72 jam. Penilaian lama rawat inap dilakukan untuk melihat efektivitas golongan antibiotik menurunkan demam, menghilangkan disuria, menormalkan lekosit urin, dan menghilangkan bakteriuria [1,2,3].…”

Section: Pendahuluanunclassified

“…Menurut penelitian Tori, sebanyak 91 pasien yang mendapatkan terapi antibiotik amkoksisilin, asam pipemidinat, asam nalidiksat, ciprofloxacin, dan oflloxacin menyimpulkan bahwa kelima antibiotik menghasilkan efektifitas yang sama atau tidak ada perbedaan signifikan (p = 0,634 > 0,05). Pada beberapa kasus ISK katerisasi, tidak terdapat perbedaan keefektifan antara Levofloxacin oral 750 mg dengan ciprofloxacin oral 750 mg dalam menurunkan insiden leukosituria sebagai terapi profilaksis terhadap ISK pada pasien yang dipasang Foley catheter [1,11,12].…”

Section: Perbedaan Efektivitas Golongan Antibiotik Terhadap Lekosit Urinunclassified

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Efektivitas Antibiotik Golongan Sefalosporin Generasi Ke-3 Dibandingkan Fluroquinolon Terhadap Pasien Infeksi Saluran Kemih di RS PKU Muhammadiyah Yogyakarta

Baso

Perwitasari

Risdiana

2018

MPI

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ABSTRAK: Salah satu penyakit infeksi yang banyak dijumpai di rumah sakit adalah infeksi saluran kemih. Pemilihan antibiotik yang tidak tepat dapat menyebabkan pertumbuhan resistensi dan multipel resistensi mikroba terhadap antibiotik yang berdampak pada meningkatnya morbiditas, mortalitas, dan biaya kesehatan. Penelitian ini bertujuan untuk mengevaluasi efektivitas dan perbandingan lama rawat inap antibiotik golongan sefalosporin generasi ke-3 dan fluoroquinolon di instalasi rawat inap RS PKU Muhammadiyah Yogyakarta. Penelitian ini menggunakan rancangan kohort retrospektif pada pasien ISK periode Januari 2015 -Desember 2017. Semua data pasien yang memenuhi kriteria inklusi diambil dari catatan rekam medis pasien. Berdasarkan hasil penelitian, sebanyak 66 pasien ISK, 90,9% didominasi oleh perempuan dan 53% didominasi oleh kelompok berumur >60 tahun. Kedua golongan antibiotik tidak menunjukkan perbedaan bermakna terhadap luaran terapi muntah (p=0,178), nyeri pinggang (p=1,000), nyeri berkemih (p=0,587), dan lama rawat inap (p=0,364). Sedangkan kedua golongan antibiotik menunjukkan perbedaan bermakna terhadap luaran terapi suhu badan (p=0,001) dan lekosit urin (p=0,001). Antibiotik golongan fluoroquinolon memiliki rata-rata lama rawat inap lebih cepat 5,42 hari dibandingkan golongan sefalosporin generasi ke-3. Efektivitas antara kedua kelompok menunjukkan perbedaan yang bermakna (p<0,05) terhadap suhu badan dan lekosit urin, namun kedua kelompok tidak menunjukkan perbedaan yang bermakna (p>0,05) terhadap luaran terapi muntah, nyeri pinggang, nyeri berkemih, dan lama rawat inap.Kata kunci: infeksi saluran kemih (ISK), sefalosporin generasi ke-3, fluroquinolon, lama rawat inap ABSTRACT: One of the most common infectious diseases in a hospital is urinary tract infection. Incorrect selection of antibiotics can lead to resistance growth and multiple microbial resistance to antibiotics that have an impact on increased morbidity, mortality, and health costs. This study aims to evaluate the effectiveness and comparison of duration of 3rd generation cephalosporin antibiotics and fluoroquinolone in inpatient installation of PKU Muhammadiyah Hospital Yogyakarta. This study used a retrospective cohort design in UTI patients from January 2015 to December 2017. All patient data meeting the inclusion criteria was taken from the patient medication records. Based on the results of the study, 66 UTI patients, 90.9% were female and 53% were dominated by groups > 60 years old. The two classes of antibiotics showed no significant difference to the outcome of vomiting therapy (p = 0.178), low back pain (p = 1.000), urinary pain (p = 0.587), and length of hospitalization (p = 0.364). While the two classes of antibiotics showed significant differences to the body temperature therapy (p = 0.001) and urinary leukocytes (p = 0.001). Fluoroquinolone class antibiotics had an average length of hospitalization of 5.42 days compared with the 3rd generation cephalosporins. The effectiveness between the two groups showed a significant difference (p<...

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Perbandingan Levofloxacin dengan Ciprofloxacin Peroral dalam Menurunkan Leukosituria Sebagai Profilaksis Isk pada Kateterisasi di RSUP. Dr. M. Djamil Padang

Cited by 2 publications

References 4 publications

Quantitative Study Of Antibiotic Use In Patients With Urinary Tract Infections At Rsu X In East Jakarta 2019

Quantitative Study Of Antibiotic Use In Patients With Urinary Tract Infections At Rsu X In East Jakarta 2019

Efektivitas Antibiotik Golongan Sefalosporin Generasi Ke-3 Dibandingkan Fluroquinolon Terhadap Pasien Infeksi Saluran Kemih di RS PKU Muhammadiyah Yogyakarta

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