Perbandingan Prediktor Mortalitas Skor PRISM III dan PELOD 2 pada Anak Sakit Kritis Non Bedah

Bramantyo, Tressa Bayu; Martuti, Sri; Salimo, Harsono

doi:10.14238/sp19.5.2018.284-9

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…In addition, study in Indonesia used a PELOD-2 cut-off value of ≥20, and found that such patients had a 7.75 times greater risk of death. 21 The SOFA, a system for evaluating organ dysfunction, was recommended by the most recent consensus. 6,19 Pediatric SOFA is SOFA with adjustments.…”

Section: Discussionmentioning

confidence: 99%

Severe sepsis criteria, PELOD-2, and pSOFA as predictors of mortality in critically ill children with sepsis

Wulandari¹,

Pudjiastuti²,

Martuti³

2019

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Background Sepsis is one of the main causes of death in infants and children. Currently, it is defined as a life-threatening organ dysfunction, caused by an inflammatory response of infection. Several organ dysfunction assessment methods are available, but they are not uniformly used. Objective To compare the accuracy of three mortality predictor tools: severe sepsis criteria, pediatric logistic organ dysfunction (PELOD)-2, and pediatric sequential organ failure assessment (pSOFA), in critically ill children with sepsis. Methods This prospective cohort study was conducted in the pediatric intensive care unit (PICU) and pediatric high care unit (HCU) of dr. Moewardi Hospital, Surakarta, Central of Java. All patients who met the systemic inflammatory response syndrome (SIRS) criteria were included in our study. The exclusion criteria were congenital anomalies of heart or kidney, malignancy, or hematological abnormalities. The data were taken from laboratory and physical examinations by the physicians on duty. The outcome assessed was mortality. Results Of 30 subjects, the mean age was 22.22 (SD 29.36) months; the most common infection source was the respiratory tract, followed by gastrointestinal tract and central nervous system. Most subjects were treated in the PICU and had a mean length of stay of 8.70 (SD 11.91) days. Severe sepsis and PELOD-2 were not significant predictors of death. However, pSOFA score was a statistically significant predictor of mortality, with odds ratio 10.11 (95%CI 1.054 to 97.002; P=0.039). Conclusion Pediatric SOFA (pSOFA) is a better predictor of mortality compared to PELOD-2 and SIRS-severe sepsis. A pSOFA score ≥ 2 increases the risk of mortality by 10.11-fold.

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Section: Discussionmentioning

confidence: 99%

Severe sepsis criteria, PELOD-2, and pSOFA as predictors of mortality in critically ill children with sepsis

Wulandari¹,

Pudjiastuti²,

Martuti³

2019

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“…The PRISM score can assess the severity of a patient's disease by using its 17 components (Pollack et al, 2015). A study by Bramantyo et al at revealed that critically ill children who had a PRISM score of > 8 had a mortality rate of 3.5 folds greater than critically ill children who had a PRISM score of < 8 (Bramantyo et al, 2018).…”

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confidence: 99%

The Role of Lactate Level as Predictor of Mortality Critically Ill Children at Moewardi Hospital

Zilmi,

Pudjiastuti,

Siregar

2024

J Matern Child Health

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Background: The prevalence of mortality among critically ill children worldwide, particularly in Indonesia, remains alarmingly high. Numerous studies have indicated that elevated lactate levels serve as a significant predictor of mortality in this vulnerable population. The primary objective of this study is to elucidate the predictive value of lactate levels in determining mortality risk among critically ill children. Subjects and Method: A cohort prospective study was conducted in children aged between 1 month and 18 years old who met the criteria for critically ill children treated in the Pediatric High care unit (PHCU) of Dr. Moewardi General Hospital, Surakarta from January to June 2023. The dependent variable was the mortality. The independent variable was lactate level serum. The data were collected using questionnaire and observation sheet. The cut off point of lactate level was determined with ROC curve. Results: Among thirty critically ill pediatric patients, 43.3% died, while 56.7% survived. The deceased predominantly comprised females, with a mean age of 5.62 years (SD= 4.14). The mean lactate levels of those who died in the first hour, 6 hours, and 24 hours (Mean= 2.94; SD= 0.90) with a cut-off value of ≥2.35 mmol/L, (Mean= 3.20; SD= 0.50) with a cut-off value of ≥ 2.35 mmol/L and (Mean= 3.65; SD= 0.53) with a cut-off value of ≥2.95 mmol/L, respectively. The 24th hours lactate levels (persistence hyperlactatemia) had the highest sensitivity (92.3%) and specificity (100%) for predicting mortality (p<0.001). Conclusion: In critically ill children, lactate level of ≥2.95 mmol/L is a good predictor of mortality. Keywords: lactate level, mortality, critically ill children. Correspondence: Reza Ervanda Zilmi. Department of Pediatrics, Sebelas Maret University/Dr. Moewardi General Hospital, Surakarta, Central Java, Indonesia. Kolonel Sutarto Street No. 132, Surakarta, Indonesia. email: zilmiervanda@gmail.com Phone: 081258038925.

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Perbandingan Prediktor Mortalitas Skor PRISM III dan PELOD 2 pada Anak Sakit Kritis Non Bedah

Cited by 2 publications

References 9 publications

Severe sepsis criteria, PELOD-2, and pSOFA as predictors of mortality in critically ill children with sepsis

Severe sepsis criteria, PELOD-2, and pSOFA as predictors of mortality in critically ill children with sepsis

The Role of Lactate Level as Predictor of Mortality Critically Ill Children at Moewardi Hospital

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