Objectives
Mindfulness-based interventions (MBIs) are effective in reducing anxiety and depression. Yet their impact on perceived stress among clinical nurses and nursing students remains less explored. This study synthesizes evidence on the effects of MBIs in mitigating perceived stress within this high-stress professional group.
Methods
We systematically searched two databases and identified studies evaluating the effects of mindfulness on perceived stress. Standardized mean differences (SMDs) were calculated using random-effects models. Thirty-six studies involving 2,201 participants were included. Separate meta-analyses were conducted for (1) one-sample pre-post designs and (2) intervention-control designs. Subgroup analyses examined control type (active vs. non-active), intervention mode (instructor-led vs. self-directed), and intervention setting (workplace vs. non-workplace). Sensitivity analyses were performed to assess the robustness of findings.
Results
Mindfulness interventions significantly reduced perceived stress, with medium effects in one-sample pre-post studies (SMD = -0.54 [-0.77, -0.31]) and small effects in intervention-control studies (SMD = -0.21 [-0.37, -0.05]). Subgroup analyses revealed stronger effects for instructor-led interventions, workplace settings, and non-active controls. Sensitivity analyses confirmed the stability of findings, with no single study disproportionately influencing the pooled effect sizes.
Conclusions
This meta-analysis reaffirms the efficacy of MBIs in reducing perceived stress among clinical nurses and nursing students. These findings highlight the potential of tailored MBIs to promote mental health and resilience in nursing professionals, while underscoring the need for further robust, region-specific randomized controlled trials to refine intervention strategies and assess long-term impacts.
Preregistration
This systematic review/meta-analysis was preregistered in PROSPERO (CRD42024509223)