Perception to COVID-19 epidemic and acceptance of vaccination among healthcare workers in Beijing: a survey before the completion of COVID-19 vaccine phase III clinical trials

Abstract

Background: Covid-19 vaccine research and development is progressing and expected to be put into use in a predictable time, we aimed to learn the awareness and acceptance of the new vaccine by healthcare workers (HCWs) in Beijing, China. Methods: A cross-sectional survey was conducted to investigate HCWs including doctors, nurses and technicians from sixty hospitals in Beijing to obtain the perception of COVID-19 epidemic and the attitudes towards vaccination before before the completion of vaccine phase III clinical trials. Multivariate analysis was applied to evaluate the associated factors with intention to get vaccination.Results: A total of 8040 HCWs was recruited. 67.1% reported they would get vaccination, others said unsure or would not. Half of the HCWs were unsure whether the outbreak in China would come back and the global epidemic would last for a long time. 67.6% agreed the epidemic can be prevented by vaccination. Positive associated factors with willingness to get vaccination were mainly included epidemic situation prognosis, perception of disease severity, self infection risk and disease can be prevented by vaccine, etc. Two positive factors of “wanted the vaccine free of charge” (OR:5.807, 95%CI:5.083-6.635, P<0.001) and “believed vaccine approved for license have been fully evaluated in clinical trials” (OR:4.485, 95%CI:3.849-5.227, P<0.001) were strongly associated with willingness to get vaccination, while two factors of “highest academic degree” (OR:0.840, 95%CI:0.772-0.914, P<0.001) and “professional ranks and titles” (OR:0.930, 95%CI:0.865-1.000, P=0.049) were negative associated .Conclusions: A little above moderate willingness to get COVID-19 vaccination was found among HCWs in Beijing before the vaccine being licensed. Free vaccination strategy should be considered to implement, effective measures should be taken to remove barriers and convey correct information through appropriate ways to enhance the acceptance of COVID-19 vaccination among HCWs in China.

Acceptability of coronavirus disease 2019 vaccination among Indian health-care professionals

“…where 68.6% of the health-care workers were willing to get the COVID-19 vaccine [ 11 ]. Similar results were found in studies done in Romania in which 69% agreed with the COVID-19 vaccine [ 12 ] and Beijing where 67.1% reported that they would get vaccinated [ 13 ].…”

The Willingness to Receive COVID-19 Vaccine and Its Associated Factors: “Vaccination Refusal Could Prolong the War of This Pandemic” – A Systematic Review

“… 36 Kanyike et al 71 2021 600 Medical Students CS Uganda 37.3% Gender (female), marital status (single), perceived risk of getting COVID-19 in the future, receiving any vaccine in the past 5 years, and COVID-19 vaccine hesitancy. 37 Luodan et al 44 2020 8040 HCWs CS China 67.1% Perception of disease severity, self-infection risk and disease can be prevented by vaccine. 38 Machida et al 61 2021 2956 Adults (20 to 79 years) CS Japan 62.1% Gender, age, income level, perceived effectiveness of the COVID-19 vaccine, and willingness to protect others by getting oneself vaccinated.…”

“…Furthermore, the study reported that factors such as perceived risk of COVID-19, 30 , 31 , 34 , 44 , 47 , 50 , 51 , 53 , 58 , 59 , 68–71 trust in healthcare system, 46 , 51 health insurance, 31 , 48 norms, 31 , 65 attitude towards a vaccine, 31 , 55 , 58 perceived benefit of vaccine, 31 , 40 , 46 , 65 , 70 perceived vaccine barriers, 31 , 40 , 70 self-efficacy, 31 up-to-date on vaccinations, 32 being tested for COVID-19 in the past, 32 , 72 responsibility, 39 perceived efficacy of the COVID-19 vaccination, 41 , 47 use of social media for COVID-19 vaccine-related information, 41 recommended for vaccination, 34 political leaning, 34 perceived severity of COVID-19, 34 , 44 , 46 , 70 , 74 perceived effectiveness of a COVID-19 vaccine, 34 , 43 , 59 , 61 belief that vaccination makes them feel less worried about COVID-19, 59 believing in mandatory COVID-19 vaccination, 50 perceived potential vaccine harms, 34 , 42 , 53 , 58 presence of chronic disease, 45 , 48 , 60 previously received an influenza vaccine, 43 , 45 , 47 <...>…”

“…Concerning to the marital status; this could also affect the willingness of the individual towards this vaccine, while married individuals have relatively a feeling of more responsible because of their collective family responsibilities. Furthermore, the study reported that factors such as perceived risk of COVID-19, 30,31,34,44,47,50,51,53,58,59,[68][69][70][71] trust in healthcare system, 46,51 health insurance, 31,48 norms, 31,65 attitude towards a vaccine, 31,55,58 perceived benefit of vaccine, 31,40,46,65,70 perceived vaccine barriers, 31,40,70 self-efficacy, 31 up-to-date on vaccinations, 32 being tested for COVID-19 in the past, 32,72 responsibility, 39 perceived efficacy of the COVID-19 vaccination, 41,47 use of social media for COVID-19 vaccine-related information, 41 recommended for vaccination, 34 political leaning, 34 perceived severity of COVID-19, 34,44,46,...…”

“…The study design of all these studies were cross-sectional. Nine studies were done in the United States, [30][31][32][33][34][35][36][37][38] nine studies were done in China, [39][40][41][42][43][44][45][46][47] one study was done in Australia, 48 four studies were done in Saudi Arabia, [49][50][51][52] one study was done in Kuwait, 53 one study was done in England, 54 one study was done in Congo, 55 one study was done in Greece, 56 two studies were done in UK, 57,58 one study was done in Malaysia, 59 two studies were done in Japan, 60,61 one study was done in Israel, 62 one study was done in Bangladesh, 63 one study was done in Jordan, 64 one study was done in Iran, 65 one study was done in Italy, 66 one study was done in Ethiopia, 67 two studies were done in France, 68,69 one study was done in Vietnam, 70 one study was done in Uganda, 71 one study was done in Pakistan, 72 one study was done in Nigeria, 73 an...…”