Percutaneous management of bile-plug syndrome: a case report

Association of N-acetylcysteine and glucagon during percutaneous cholangiography in the treatment of inspissated bile syndrome

“…In a significant proportion of neonates, no recognized predisposing factors are present; however, in some situations, it is a complication of infection, hepatocellular damage, cystic fibrosis, hemolytic disorders, or total parenteral nutrition. Spontaneous resolution is possible, but if recovery does not occur, surgery [2] or intervention radiology [3] is required. Percutaneous cholangiography confirms the dilatation of the biliary tract, highlights the level of the obstruction, identifies Inspissated bile syndrome the obstruction based on the filling defects, and permits sampling of the bile for analysis.…”

Pediatric Biliary Interventions in the Native Liver

“…These conditions are uncommon causes of cholestasis in infants. 38,39 Predisposing factors include cystic fibrosis, parenteral nutrition, hemolysis, and conditions producing hepatocellular injury such as CMV infection. 38 On US, typical findings include biliary ductal dilation with echogenic material within the bile ducts and sometimes in Fig.…”

“…40,41 Although in some cases obstruction may resolve spontaneously or with oral ursodeoxycholic acid, surgery has been the mainstay of treatment. 38,[40][41][42] There is a report of successful percutaneous management of cholestatic jaundice believed to be caused by bile plug syndrome in a 5-monthold. In this case, a cholecystostomy catheter was placed for biliary drainage with subsequent balloon dilation of the distal CBD.…”

“…In this case, a cholecystostomy catheter was placed for biliary drainage with subsequent balloon dilation of the distal CBD. 38…”

One-stage laparoscopic surgery for inspissated bile syndrome: case report and review of surgical techniques

“…Besides the possibility for irrigation of the bile ducts, laparoscopy and intraoperative cholangiography are suitable to rule out biliary tract malformations as a reason for cholestasis when combined with a liver biopsy. Several procedures are described for clearance of obstructed bile ducts: percutaneous management under sedation with transhepatic puncture of the gall bladder and introduction of a wire and a balloon dilator has recently been reported (Duman et al 2011). The majority of authors describe laparoscopic aided cholecystostomy under anesthesia with placement of a catheter into the gall bladder for repeated irrigation with saline (Gao et al 2011) or ursodesoxycholic acid (Gunnarsdottir et al 2008; Lieber et al 2012).…”