Percutaneous polymethylmethacrylate vertebroplasty in the treatment of pain induced by metastatic spine tumor

Effectiveness of percutaneous vertebroplasty in cases of vertebral metastases

“…Mikami et al [13] state that the preoperative mean VAS score was reduced from 7.3 to postoperative 1.9 with PV performed on 141 metastatic vertebras of 69 patients. Tseng et al [4] showed that the preoperative mean VAS score of 8.1 decreased to 3.8 one day after and to 2.8 six months after PV. Alvarez et al [11] reported that the preoperative VAS score of 9.1 decreased to 3.2 immediately after and to 2.8 three months after PV.…”

“…Decrease in tumor progression or recurrence can be obtained from the antitumoral effect of the cement [18]. In order to achieve vertebral stiffness after PV, an average of 3.5 mL volume of PMMA is sufficient [4,19]. To achieve vertebral stiffness after PV, Tseng et al used [4] 5.16 ± 1.63 mL, Chew et al [5] used less than 5 mL, and Barragán-Campos et al [7] used 4.7 ± 1.55 mL of PMMA.…”

“…Percutaneous vertebroplasty (PV) is a minimally invasive procedure with polymethylmethacrylate (PMMA) bone cement injection into the vertebral body [4]. It is one of the modalities accepted for treating vertebral fractures caused by osteoporosis, malignancies and trauma [5].…”

Effectiveness of percutaneous vertebroplasty in patients with multiple myeloma having vertebral pain

“…The median duration per session was 43.5 minutes (range, 18-78). The median volume of PMMA injected into the vertebral body during PV was 6 mL (range, [3][4][5][6][7][8][9][10].…”

Radiotherapy in palliative treatment of painful bone metastases

“…MR-guided focused ultrasound surgery and percutaneous polymethylmethacrylate vertebroplasty) that offer a remarkable advantage of effective and immediate pain relief with few complications, should be considered. 17,60,61 Malignant spinal cord compression asks for the most urgent surgical intervention. The decision on treatment modalities or combination of different therapies (surgery with postoperative radiotherapy, radiotherapy only, specific therapies according to tumour type) should be carried out on multidisciplinary setting according to the neurological, oncological, orthopedical and systemic principles.…”