HighlightsGastrostomy can be a necessity in a variety of clinical situations either for nutrition or for gastrointestinal discharge.There are two major techniques: open gastrostomy and minimally invasive gastrostomy.We describe herein a technique of laparoscopic-assisted percutaneous endoscopic gastrostomy (LAPEG) in 2 cases with different primary pathologies and unsuccessful attempt of Percutaneous endoscopic gastrostomy as the first intention.LAPEG might be an interesting option by minimizing the risk of intestinal injury and might be a faster and easier procedure than laparoscopic gastrostomy, and should be considered for selected cases.