Trumpetcreeper (Campsis radicans) is a native, perennial, weedy vine of pastures, row crops, fence rows, and right-of-ways throughout most of the eastern United States. Field and greenhouse studies were conducted in 2008 and 2009 near Newport, TN, and in Knoxville, TN, to evaluate aminocyclopyrachlor-methyl and aminopyralid alone and in mixtures with 2,4-D and diflufenzopyr for selective trumpetcreeper control when applied postemergence in an abandoned nursery. These treatments were compared with commercial standards of dicamba and a prepackaged mixture of triclopyr plus 2,4-D. In the field, aminocyclopyrachlor-methyl alone controlled trumpetcreeper 77% to 93%, while aminopyralid alone only controlled trumpetcreeper 0% to 20% by 12 months after treatment (MAT). The addition of diflufenzopyr or 2,4-D to aminocyclopyrachlor-methyl did not improve trumpetcreeper control in the field; however, the addition of 2,4-D to aminopyralid improved control of trumpetcreeper from 50% to 58%. All aminocyclopyrachlor-methyl treatments controlled trumpetcreeper greater than or equal to dicamba and the prepackaged mixture of triclopyr plus 2,4-D. In the greenhouse, aminocyclopyrachlor and aminocyclopyrachlor-methyl applied at 8.75 to 35 g·ha−1 controlled trumpetcreeper 58% to 72% by 1 MAT. When both herbicides were applied at 70 g·ha−1, aminocyclopyrachlor controlled trumpetcreeper 64%, while aminocyclopyrachlor-methyl controlled trumpetcreeper 99%, similar to dicamba.