2022
DOI: 10.33448/rsd-v11i2.25672
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Perfil epidemiológico de pacientes com COVID-19 em UTI de Hospital de Referência do Sul do Brasil: a idade como fator de risco para pior desfecho

Abstract: Introdução: A epidemia do coronavírus, causada pelo SARS-CoV 2, atingiu a marca de 5,1 milhões de mortes em todo o mundo até novembro de 2021. O vírus acometeu diferentes perfis da população, porém não se tem dados referentes às características demográficas dos pacientes internados em terapia intensiva. Objetivo: Descrever o perfil dos pacientes que foram tratados com COVID-19 na Unidade de Terapia Intensiva do Hospital Universitário e avaliar quais variáveis tiveram mais relação com mortalidade desses pacient… Show more

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Cited by 7 publications
(8 citation statements)
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“…Notably, determining the clinical-epidemiological and laboratory profiles of COVID-19 patients can provide valuable information for a multidisciplinary healthcare team for more assertive clinical management, better resource allocation, and improved survival of patients admitted with COVID-19 in the ICU ( 44 , 45 ). In this study, when multifactorial variables were correlated using regression analysis, the male sex had a higher chance of death, consistent with previous studies ( 46 , 47 ). Furthermore, male-specific variables such as hypogonadism and low testosterone levels have been linked to the development of comorbidities that increase mortality from COVID-19, including type 2 diabetes, obesity, and cardiovascular disease ( 46 ).…”
Section: Discussionsupporting
confidence: 91%
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“…Notably, determining the clinical-epidemiological and laboratory profiles of COVID-19 patients can provide valuable information for a multidisciplinary healthcare team for more assertive clinical management, better resource allocation, and improved survival of patients admitted with COVID-19 in the ICU ( 44 , 45 ). In this study, when multifactorial variables were correlated using regression analysis, the male sex had a higher chance of death, consistent with previous studies ( 46 , 47 ). Furthermore, male-specific variables such as hypogonadism and low testosterone levels have been linked to the development of comorbidities that increase mortality from COVID-19, including type 2 diabetes, obesity, and cardiovascular disease ( 46 ).…”
Section: Discussionsupporting
confidence: 91%
“…Furthermore, male-specific variables such as hypogonadism and low testosterone levels have been linked to the development of comorbidities that increase mortality from COVID-19, including type 2 diabetes, obesity, and cardiovascular disease ( 46 ). Additionally, evidence suggests that unbalanced testosterone levels may facilitate infection and disease progression in men because of their impact on the expression of the SARS-CoV-2 receptor, angiotensin-converting enzyme-2, and major fusogenic transmembrane serine protease 2 under regular transcription by androgens ( 47 , 48 ).…”
Section: Discussionmentioning
confidence: 99%
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“…A cross-sectional study carried out with 93 patients from an ICU in southern Brazil, aimed at describing the profile of the patients hospitalized due to COVID-19 and evaluating which variables were related to mortality. 50.5% of the patients were male, with a mortality rate of 69.3% 24 .…”
Section: Discussionmentioning
confidence: 97%
“…Estudos similares em outras localidades do Brasil demonstraram dados semelhantes quanto ao sexo, idade e presença de comorbidades destes pacientes (KRUGER et al, 2022; Brazilian Journal of Health Review, Curitiba, v. 6, n. 6, p. 28935-28950, nov./dec., 2023 OLIVEIRA et al, 2021), corroborando também com demais pesquisas em âmbito mundial (LOBO-VALBUENA et al, 2021;NASIR et al, 2021).…”
Section: Discussionunclassified