Performance evaluation of four 25-hydroxyvitamin D assays to measure 25-hydroxyvitamin D2

Freeman, James E.; Wilson, Kimberly; Spears, Ryan; Shalhoub, Victoria; Sibley, Paul

doi:10.1016/j.clinbiochem.2015.05.021

Cited by 48 publications

(38 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Otros métodos entre los que se destaca el DiaSorin Liaison 25 OH Vitamina D Total, empleado en este estudio, son ampliamente utilizados a nivel mundial en la determinación sérica de vitamina D para estudios poblacionales con resultados confiables. 24,26 La falta de unidad en los valores de referencia utilizados para la clasificación de las deficiencias e insuficiencias en los diferentes estudios también causa una gran variabilidad en los reportes e impide un adecuado análisis de la situación a nivel regional. 27,28 En general, habrá que considerar que la insuficiencia de vitamina D corresponde a valores séricos inferiores a 30 ng/ml y que la deficiencia a valores inferiores a 20 ng/ml son los criterios más aceptados a nivel mundial, 13 aunque no necesariamente son considerados los mejores, ya que algunos autores asocian niveles séricos más altos de esta vitamina con efectos protectores contra enfermedades como el cáncer.…”

Section: Cuadro Iunclassified

Estado de la 25-hidroxivitamina D sérica en niños sanos menores de 10 años del área metropolitana de Barranquilla

Acosta-Bendek¹,

Sánchez-Majana

Fonseca-Galé³

et al. 2017

Salud Publica Mex

View full text Add to dashboard Cite

Objetivo. Evaluar los niveles séricos de 25-hidroxivitamina D (25-OH-D) en niños sanos menores de 10 años del área metropolitana de Barranquilla (AMB). Material y métodos. Estudio descriptivo de corte transversal, que evaluó los niveles séricos de 25-OH-D en 360 niños del AMB en los años 2014-2015. Resultados. El valor promedio de 25-OH-D en la población estudiada fue 32.23±8.56 ng/mL; 46.38% de los niños tenía niveles de vitamina D considerados insuficientes (<30 ng/mL) y 3.05% mostro deficiencia (<20 ng/mL). Soledad y Puerto Colombia fueron los municipios con mayor población en esta condición. Conclusiones. Es necesario generar programas de suplementación nutricional y fomentar estilos de vida que permitan, de forma segura, mejorar los niveles de vitamina D en la población.

show abstract

Section: Cuadro Iunclassified

Estado de la 25-hidroxivitamina D sérica en niños sanos menores de 10 años del área metropolitana de Barranquilla

Acosta-Bendek¹,

Sánchez-Majana

Fonseca-Galé³

et al. 2017

Salud Publica Mex

View full text Add to dashboard Cite

show abstract

“…The different results of the mentioned studies might also be due to different confounding variables and different measurement methods [29] for the 25(OH)D concentrations. Only the study by YAO et al [8] used the same assay to measure vitamin D concentrations as was used in the GINIplus and LISAplus studies.…”

Section: Discussionmentioning

confidence: 98%

Higher serum 25(OH)D concentrations are associated with improved FEV₁and FVC in adolescence

et al. 2017

View full text Add to dashboard Cite

Vitamin D plays a role in the development of the immune system and the lung, as well as in airway remodelling. Therefore, this study investigated the association between serum 25-hydroxyvitamin D (25(OH)D) concentrations and spirometric lung function parameters at age 15 years.In the German birth cohorts GINIplus and LISAplus, lung function testing by spirometry and 25(OH)D measurements were performed during the 15-year follow-up examinations. Valid lung function measurements pre- and/or post-bronchodilation and serum 25(OH)D concentrations, which were adjusted for the date of blood sampling to account for seasonal variability, were available for 2607 adolescents. Associations between 25(OH)D concentrations and spirometric parameters were analysed using generalised additive models adjusted for confounding factors.Serum 25(OH)D concentrations were significantly associated with forced vital capacity (FVC), forced expiratory volume in 1 s (FEV) and FEV/FVC measured before bronchodilation after adjustment for potential confounders: FEV increased by 10 mL (95% CI 2-17), FVC by 20 mL (95% CI 12-28) and FEV/FVC decreased by 0.177% (95% CI -0.286 to -0.067) per 10 nmol·L increase in 25(OH)D concentrations. Flow rates (forced expiratory flow rates at 25, 50 and 75% of exhaled FVC (FEF, FEF, FEF) and mean flow rate between 25 and 75% of FVC (FEF)) were not associated with vitamin D. Similar associations were observed for lung function parameters measured after bronchodilation.Vitamin D concentrations are positively associated with volume-related lung function parameters pre- and post-bronchodilation, suggesting structural changes in peripheral airways.

show abstract

“…The detection limit was <10.0 nmol/L, with intra‐ and interassay coefficients of variation of 4.2 and 11.9%, respectively. This assay showed comparable performance with the liquid‐chromatography tandem mass spectrometry method. A mean value of 5.0 nmol/L was taken for results reported as <10.0 nmol/L.…”

Section: Methodsmentioning

confidence: 99%

Association between serum 25‐hydroxyvitamin D and glycated hemoglobin levels in type 2 diabetes patients with chronic kidney disease

Lim

Kang

et al. 2017

J of Diabetes Invest

View full text Add to dashboard Cite

Aims/IntroductionVitamin D is suggested to influence glucose homeostasis. An inverse relationship between serum 25‐hydroxyvitamin D (25[OH]D) and glycemic control in non‐chronic kidney disease (CKD) patients with type 2 diabetes was reported. We aimed to examine this association among type 2 diabetes patients with CKD.Materials and MethodsA total of 100 type 2 diabetes participants with stage 3–4 CKD were recruited. Blood for glycated hemoglobin (HbA1c), serum 25(OH)D, renal and lipid profiles were drawn at enrollment. Correlation and regression analyses were carried out to assess the relationship of serum 25(OH)D, HbA1c and other metabolic traits.ResultsA total of 30, 42, and 28% of participants were in CKD stage 3a, 3b and 4, respectively. The proportions of participants based on ethnicity were 51% Malay, 24% Chinese and 25% Indian. The mean (±SD) age and body mass index were 60.5 ± 9.0 years and 28.3 ± 5.9 kg/m2, whereas mean HbA1c and serum 25(OH)D were 7.9 ± 1.6% and 37.1 ± 22.2 nmol/L. HbA1c was negatively correlated with serum 25(OH)D (r s = −0.314, P = 0.002), but positively correlated with body mass index (r s = 0.272, P = 0.006) and serum low‐density lipoprotein cholesterol (P = 0.006). There was a significant negative correlation between serum 25(OH)D and total daily dose of insulin prescribed (r s = −0.257, P = 0.042). Regression analyses showed that every 10‐nmol/L decline in serum 25(OH)D was associated with a 0.2% increase in HbA1c.ConclusionsLower serum 25(OH)D was associated with poorer glycemic control and higher insulin use among multi‐ethnic Asians with type 2 diabetes and stage 3–4 CKD.

show abstract

Performance evaluation of four 25-hydroxyvitamin D assays to measure 25-hydroxyvitamin D2

Abstract: The bias results obtained for the Siemens ADVIA Centaur assay and Roche ELECSYS assay were slightly lower than those for the DiaSorin LIAISON assay and the Abbott ARCHITECT assay, but all 25(OH)D assays demonstrated acceptable performance.

Cited by 48 publications

References 42 publications

Estado de la 25-hidroxivitamina D sérica en niños sanos menores de 10 años del área metropolitana de Barranquilla

Estado de la 25-hidroxivitamina D sérica en niños sanos menores de 10 años del área metropolitana de Barranquilla

Higher serum 25(OH)D concentrations are associated with improved FEV₁and FVC in adolescence

Association between serum 25‐hydroxyvitamin D and glycated hemoglobin levels in type 2 diabetes patients with chronic kidney disease

Contact Info

Product

Resources

About

Performance evaluation of four 25-hydroxyvitamin D assays to measure 25-hydroxyvitamin D2

Abstract: The bias results obtained for the Siemens ADVIA Centaur assay and Roche ELECSYS assay were slightly lower than those for the DiaSorin LIAISON assay and the Abbott ARCHITECT assay, but all 25(OH)D assays demonstrated acceptable performance.

Cited by 48 publications

References 42 publications

Estado de la 25-hidroxivitamina D sérica en niños sanos menores de 10 años del área metropolitana de Barranquilla

Estado de la 25-hidroxivitamina D sérica en niños sanos menores de 10 años del área metropolitana de Barranquilla

Higher serum 25(OH)D concentrations are associated with improved FEV1and FVC in adolescence

Association between serum 25‐hydroxyvitamin D and glycated hemoglobin levels in type 2 diabetes patients with chronic kidney disease

Contact Info

Product

Resources

About

Higher serum 25(OH)D concentrations are associated with improved FEV₁and FVC in adolescence