People with Cerebral Palsy (CP) are typically less physically active than the general population and, consequently, are at increased risk of a range of preventable diseases. Evidence indicates that low-moderate doses of physical activity can reduce disease risk, and improve clinically important outcomes including fitness and function. The effect of high doses of physical activity have not been thoroughly evaluated in people with CP, however in the general population it is known that doses of physical activity much higher than those recommended as guidelines elicit the greatest health gains. Para athletes with CP who compete in Para Sport typically engage in 'performance-focused' sports training-a form of physical activity which is primarily undertaken for the purpose of enhancing performance in a chosen sport and which is, typically, relatively high-dose. Anecdotally, many Para athletes report that participation in performance-focused sports training confers meaningful clinical benefits which exceed those reported in the literature, however supporting scientific evidence is lacking. The aim of this thesis is to investigate the 5 Submitted manuscripts included in this thesis No manuscripts submitted for publication. Other publications during candidature No other publications. Contributions by others to the thesis Associate Professor Sean Tweedy-Support in the conception and design of the overall thesis. Support in the development of methods, and in the collection and interpretation of data. Critical revision and editing of all chapters of the thesis. Dr Emma Beckman-Support in the development of methods and interpretation of results. Critical revision and editing of Chapters 3, 4 and 5 of the thesis. Dr Mark Connick-Support in the development of methods, data analysis and interpretation of results. Critical revision of Chapters 3 and 5 of the thesis. Associate Professor Leanne Johnston-Support in the development of methods, interpretation of results. Provided advice regarding fidelity of the interventions delivered as part of the program of research. Critical revision and editing of Chapters 2, 3, 4 and 5 of the thesis. 6 Statement of parts of the thesis submitted to qualify for the award of another degree No works submitted towards another degree have been included in this thesis.