In order to help students learn and master SCM serial interface technology, one self-teaching circuit board on serial interface technology has been designed. This paper mainly discusses the design method of the circuit board. First of all, the on-system programming module, I 2 C module, SPI module, 1-Wire bus module, serial keyboard and digital tube and LCD display interface module are introduced in detail; then the design method of on-system programming software is discussed. With this circuit board, students can easily master all kinds of serial interface technology usually used in the development of single chip microcomputer. It has been used by many colleges and universities and SCM technology training, the good teaching effect has been achieved.