Performance modeling of a wearable brain PET (BET) camera

Schmidtlein, Charles; Turner, James N.; Thompson, Michael O.; Mandal, Krishna C.; Häggström, Ida; Zhang, Jiahan; Humm, John L.; Feiglin, David; Król, Andrzej

doi:10.1117/12.2217020

Cited by 6 publications

(5 citation statements)

References 11 publications

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“…In both previous cases the achieved sensitivity at the FOV centre is lower than the one we see in the FOV centre of our helmet. The prototype proposed in [33] is analytically compared with a cylindrical architecture having the same radius and made out with the same scintillators. For the estimation of its sensitivity, they used a line source in different media, achieving values for the helmet that are averagely 1.53 higher than the cylindrical scanner and with no significantly better values at the centre of the FOV.…”

Section: Jinst 15 C05071 4 Discussionmentioning

confidence: 99%

Simulation study on sensitivity performance of a helmet-shaped brain PET scanner based on the Plug&Imaging detector design

et al. 2020

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A: Novel design solutions for the functional imaging of patients suffering of motion disorders represent the frontiers of nuclear medicine and neurology. We report the design and simulation of a novel digital helmet-shaped Positron Emission Tomography system with transverse and longitudinal Field Of View of 205 mm and 283.8 mm respectively. We calculated the sensitivity of the system in simulation in accordance to NEMA standards. The device shows a 45.5% to 70.2% increase around the centre of the Field Of View with respect to a conventional cylindrical brain PET system. Furthermore, the sensitivity has a constant profile in a wide area across the Field Of View. In addition, in order to verify the correctness of the estimation, we compared the simulated and experimental sensitivities of a previously designed brain PET system, which were found in good 1Corresponding author.

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Section: Jinst 15 C05071 4 Discussionmentioning

confidence: 99%

Simulation study on sensitivity performance of a helmet-shaped brain PET scanner based on the Plug&Imaging detector design

et al. 2020

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“…8). Several groups have also developed wearable brain imaging systems that are supported on the subject's head so as to enable acquisition during free movement of the subject [59][60][61]. These clearly depend on availability of compact, light-weight technology.…”

Section: Petmentioning

confidence: 99%

Advances in clinical molecular imaging instrumentation

Hutton

Erlandsson

Thielemans

2018

Clin Transl Imaging

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In this article, we describe recent developments in the design of both single-photon emission computed tomography (SPECT) and positron emission tomography (PET) instrumentation that have led to the current range of superior performance instruments. The adoption of solid-state technology for either complete detectors [e.g., cadmium zinc telluride (CZT)] or read-out systems that replace photomultiplier tubes [avalanche photodiodes (APD) or silicon photomultipliers (SiPM)] provide the advantage of compact technology, enabling flexible system design. In SPECT, CZT is well suited to multi-radionuclide and kinetic studies. For PET, SiPM technology provides MR compatibility and superior time-of-flight resolution, resulting in improved signal-to-noise ratio. Similar SiPM technology has also been used in the construction of the first SPECT insert for clinical brain SPECT/MRI.

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“…Wearable brain PET was another spherical PET design presented by Schmidtlein et al in 2016. They showed using analytical and Monte Carlo simulation, that their spherical cap model can improve the noise-equivalent count rate (NEC) without degradation of the spatial resolution when compared to equivalent cylindrical brain PET [6].…”

Section: Introductionmentioning

confidence: 99%

Concept design and Monte Carlo performance evaluation of HeadphonePET: a novel brain-dedicated PET system based on partial cylindrical detectors

et al. 2018

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In recent years, different geometries of brain-dedicated PET scanners have been developed due to the fact that there are great emerging demands for high-quality and low-cost brain-dedicated scanners. To meet the demand, we present a novel conceptual design based on a partial cylindrical detector geometry and evaluate the performance of the designed scanner.Methods and materials: The proposed design was modeled with a ring diameter of 245 mm and axial field of view (FOV) of 277 mm, thus covering the top and sides of patient's head. Detection efficiency of our new optimized design, which we refer to as HeadphonePET, was calculated against conventional cylindrical brain PET and whole-body positron scanners.Also, in order to measure the system spatial resolution and evaluate image quality, different simulated array sources and their related projections were extracted. Finally the obtained projections were reconstructed using analytical and iterative algorithms.

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Performance modeling of a wearable brain PET (BET) camera

Cited by 6 publications

References 11 publications

Simulation study on sensitivity performance of a helmet-shaped brain PET scanner based on the Plug&Imaging detector design

Simulation study on sensitivity performance of a helmet-shaped brain PET scanner based on the Plug&Imaging detector design

Advances in clinical molecular imaging instrumentation

Concept design and Monte Carlo performance evaluation of HeadphonePET: a novel brain-dedicated PET system based on partial cylindrical detectors

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