Performance of a New-Generation Extended Depth of Focus Intraocular Lens—A Prospective Comparative Study

Abstract

Purpose: The aim was to study the visual performance of a new refractive extended depth of focus (EDOF) intraocular lens (IOL). Design: Prospective, comparative study. Methods: Consenting patients with age-related cataract willing for bilateral cataract surgery within 2 weeks were implanted with the Supraphob EDOF IOL and those willing for 1 eye surgery were implanted with a monofocal IOL. The uncorrected and best-corrected distance, intermediate and near visual acuity, and contrast sensitivity were evaluated at 1 and 3 months postoperatively. We also inquired about glare, halos, difficulties in night driving, requirement for spectacles, and overall satisfaction with vision. Results: The Supraphob EDOF group (n = 72 eyes) and the monofocal IOL group (n = 54 eyes) were comparable with respect to all preoperative parameters including biometry, visual acuity, and cataract status. The mean age of participants was 58.4 ± 10.6 years. Both groups had similar distance vision but the EDOF group had significantly better intermediate (0.2 ± 0.2 logMAR vs 0.75 ± 0.19 logMAR, P < 0.001) and near vision (median = N6 vs N12, P < 0.001) compared to the monofocal group at 3 months. The contrast sensitivity was similar in both groups. Patients in the EDOF IOL group had much greater satisfaction for intermediate and near vision. Less than 10% patients reported glare, halos, and difficulty in driving at night in the EDOF group. Conclusions: The Supraphob EDOF IOL was effective in improving the distance, intermediate and near vision in majority of patients, and retained good contrast sensitivity with most patients reporting excellent satisfaction.

Clinical Outcomes with a Novel Extended Depth of Focus Presbyopia-Correcting Intraocular Lens: Pilot Study

“…Specifically, in the current series, mean 3-month postoperative monocular UDVA and UNVA values of 0.11 ± 0.17 and 0.14 ± 0.22 logMAR were obtained, respectively. This finding is consistent with the results of other studies evaluating the performance of other types of EDOF IOLs, 7,8,13,[17][18][19] although it should be noted that 4 micro-monovision cases were included in our sample. Giers et al 18 evaluated an EDOF IOL also based on induction of controlled levels of spherical aberration (MiniWell Ready), obtaining median monocular UDVA and UNVA values of 0.13 and 0.14 logMAR, respectively, at 2-4 months after its implantation.…”

“…1,2,4,[7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] A common finding with all types of EDOF IOLs is an effective visual restoration at intermediate vision, but the level of near vision achieved varies significantly among IOL models. 1,2,4,[7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] A novel recent EDOF approach has been developed for presbyopia correction based on the combination of primary and secondary spherical aberrations of opposite signs with a transition zone to a peripheral monofocal area (Synthesis PLUS, Cutting Edge, Montpellier, France). The theoretical aim of this new design is to deliver continuous high-contrast vision from distance to intermediate vision, while maintaining a functional level of near vision and preserving the ocular optical quality within an acceptable range to avoid the induction of light disturbances, such as halos, glare or starbursts.…”

A clinical study to assess feasibility, acceptance, and outcome of multifocal intraocular lens in patients with bilateral immature cataract at a tertiary eye care institute

“…The EDOF lenses are found to offer better contrast sensitivity and decreased spectacle dependence for distance, intermediate, and near vision with lesser visual disturbances compared to bifocal IOLs. [ 7 8 ] There is a lack of literature regarding the feasibility and acceptability of the multifocal IOLs in patients, especially in Indian settings, thus there was a necessity to carry out research for the same. In the present study, out of 1691 patients with age-related senile cataract, only 920 (54.5%) were feasible.…”

<p>Binocular Visual Function in a Pre-Presbyopic Patient with Uniocular Cataract Undergoing Cataract Surgery with a Multifocal Intraocular Lens</p>

“…The trial had intended to recruit and randomize more subjects however, it was closed early due to slow recruitment and because the chosen multifocal lens had been superseded by newer IOL models. 16,17 Five subjects had completed the trial by termination; however, as a consequence of randomisation, four of these subjects had been randomised to control, receiving a monofocal IOL, only one subject received the multifocal IOL. The control participant with the baseline characteristics most alike the subject participant was selected for analyses in this case series.…”